SRP6158
EPO human
recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)
Manufacturer: Sigma Aldrich
CAS Number: 11096-26-7
Synonym(S): EP, EPO-alpha, Epoetin, Erythropoietin-alpha, MGC138142
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 μG | SRP6158-10-μG | In Stock | ₹ 65,900.70 |
SRP6158 - 10 μG
In Stock
Quantity
1
Base Price: ₹ 65,900.70
GST (18%): ₹ 11,862.126
Total Price: ₹ 77,762.826
biological source
human
recombinant
expressed in HEK 293 cells
Assay
≥95% (SDS-PAGE)
form
lyophilized
mol wt
36 kDa (monomer, glycosylated)
packaging
pkg of 10 μg
technique(s)
cell culture | mammalian: suitable
NCBI accession no.
P01588
UniProt accession no.
P01588
shipped in
dry ice
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Erythropoietin human | Sigma Aldrich | ₹ 63,658.50 | |
| | Erythropoietin human | Sigma Aldrich | ₹ 63,658.50 | |
 | 11096-26-7 | Erythropoietin | A2B Chem | -- |
Related Products
Description
- General description: The gene EPO (erythropoietin) is mapped to human chromosome 7q22.[1] It is a glycoprotein hormone. EPO is generated in fetal liver and adult kidney. However, it can also be secreted by other organs, such as the heart, brain and lungs.[2] EPO is a member of the EPO/TPO (thrombopoietin) family and is found in the plasma.[3]
- Application: EPO (erythropoietin) has been used as a component of the culture medium for cardiac stem cells.[4] In cultured cerebellar granule cells and hippocampal neurons, it has been used to study effect of EPO on glutamate release.[5] It has also been used as a component of endothelial differentiation medium.[6]
- Biochem/physiol Actions: EPO (erythropoietin) regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis.[3] It interacts with EPO receptor and is responsible for the cellular responses. EPO is expressed in many cancers, including breast cancer, renal cancer, gastric cancer, hepatocellular carcinoma and central nervous system tumors. In addition, it is a hypoxia responsive cytokine and a pro-angiogenic factor.[2] This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types.[7] It can protect from brain damages due to ischemia and enhances memory as well as cognitive ability in humans suffering from vascular dementia.[7]
- Physical form: Lyophilized from a PBS solution.
- Preparation Note: Centrifuge the vial prior to opening.
- Reconstitution: Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
biological source: human
recombinant: expressed in HEK 293 cells
Assay: ≥95% (SDS-PAGE)
form: lyophilized
mol wt: 36 kDa (monomer, glycosylated)
packaging: pkg of 10 μg
technique(s): cell culture | mammalian: suitable
NCBI accession no.: P01588
UniProt accession no.: P01588
shipped in: dry ice
biological source:
human
recombinant:
expressed in HEK 293 cells
Assay:
≥95% (SDS-PAGE)
form:
lyophilized
mol wt:
36 kDa (monomer, glycosylated)
packaging:
pkg of 10 μg
technique(s):
cell culture | mammalian: suitable
NCBI accession no.:
P01588
UniProt accession no.:
P01588
shipped in:
dry ice
biological source: human
recombinant: expressed in HEK 293 cells
Assay: ≥95% (SDS-PAGE)
form: lyophilized
mol wt: 22 kDa (monomer, non-glycosylated)
packaging: pkg of 10 μg
technique(s): cell culture | mammalian: suitable
NCBI accession no.: P01241
UniProt accession no.: __
shipped in: __
biological source:
human
recombinant:
expressed in HEK 293 cells
Assay:
≥95% (SDS-PAGE)
form:
lyophilized
mol wt:
22 kDa (monomer, non-glycosylated)
packaging:
pkg of 10 μg
technique(s):
cell culture | mammalian: suitable
NCBI accession no.:
P01241
UniProt accession no.:
__
shipped in:
__
biological source: human
recombinant: expressed in HEK 293 cells
Assay: ≥97% (SDS-PAGE)
form: lyophilized powder
mol wt: calculated mol wt 15 kDaobserved mol wt 18-23 kDa (DTT-reduced. Protein migrates due to glycosylation. Thr 103 is the predicted N-terminus .)
packaging: pkg of 10 μg
technique(s): __
NCBI accession no.: __
UniProt accession no.: P49767
shipped in: __
biological source:
human
recombinant:
expressed in HEK 293 cells
Assay:
≥97% (SDS-PAGE)
form:
lyophilized powder
mol wt:
calculated mol wt 15 kDaobserved mol wt 18-23 kDa (DTT-reduced. Protein migrates due to glycosylation. Thr 103 is the predicted N-terminus .)
packaging:
pkg of 10 μg
technique(s):
__
NCBI accession no.:
__
UniProt accession no.:
P49767
shipped in:
__
biological source: human
recombinant: expressed in HEK 293 cells
Assay: ≥92% (SDS-PAGE)
form: lyophilized powder
mol wt: calculated mol wt 25.4 kDaobserved mol wt 28-33 kDa (DTT-reduced. Protein migrates due to glycosylation. Glu 19 is the predicted N-terminus.)
packaging: pkg of 10 μg
technique(s): __
NCBI accession no.: __
UniProt accession no.: Q15848
shipped in: wet ice
biological source:
human
recombinant:
expressed in HEK 293 cells
Assay:
≥92% (SDS-PAGE)
form:
lyophilized powder
mol wt:
calculated mol wt 25.4 kDaobserved mol wt 28-33 kDa (DTT-reduced. Protein migrates due to glycosylation. Glu 19 is the predicted N-terminus.)
packaging:
pkg of 10 μg
technique(s):
__
NCBI accession no.:
__
UniProt accession no.:
Q15848
shipped in:
wet ice