C1200000

Chloramphenicol

European Pharmacopoeia (EP) Reference Standard

Manufacturer: Sigma Aldrich

CAS Number: 56-75-7

Synonym(S): D-(−)-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-β-(4-nitrophenyl)ethyl]acetamide, D-(−)-threo-2-Dichloroacetamido-1-(4-nitrophenyl)-1,3-propanediol, D-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-4-nitrophenethyl]acetamide, Chloromycetin

Select a Size

Pack Size SKU Availability Price
110 MG C1200000-110-MG In Stock ₹ 16,107.60

C1200000 - 110 MG

₹ 16,107.60

In Stock

Quantity

1

Base Price: ₹ 16,107.60

GST (18%): ₹ 2,899.368

Total Price: ₹ 19,006.968

grade

pharmaceutical primary standard

API family

chloramphenicol

manufacturer/tradename

EDQM

mp

149-153 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

OC[C@@H](NC(=O)C(Cl)Cl)[C@H](O)c1ccc(cc1)[N+]([O-])=O

InChI

1S/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9-/m1/s1

InChI key

WIIZWVCIJKGZOK-RKDXNWHRSA-N

Other Options

Image Product Name Manufacturer Price Range
31667
Chloramphenicol
Supelco ₹ 4,871.25
1107004
Chloramphenicol
Sigma Aldrich ₹ 40,756.13
C1919
Chloramphenicol
Sigma Aldrich ₹ 6,765.63 - ₹ 28,166.65
C0378
Chloramphenicol
Sigma Aldrich ₹ 3,139.25 - ₹ 1,10,728.93
C0857
Chloramphenicol
Sigma Aldrich ₹ 9,634.25 - ₹ 1,17,949.20

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Description

  • General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
  • Application: Chloramphenicol EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
  • Biochem/physiol Actions: Mode of Action: Chloramphenicol inhibits bacterial protein synthesis by blocking the peptidyl transferase step by binding to the 50S ribosomal subunit and preventing attachment of aminoacyl tRNA to the ribosome. It also inhibits mitochondrial and chloroplast protein synthesis and ribosomal formation of (p)ppGpp, de-pressing rRNA transcription. Mode of Resistance: Use of chloramphenicol acetyltransferase will acetylate the product and inactivate it. Antimicrobial Spectrum: This is a broad spectrum antibiotic against gram-positive and gram-negative bacteria, and is used mainly for ophthalmic and veterinary purposes.
  • Packaging: The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
  • Other Notes: Sales restrictions may apply.

SAFETY INFORMATION

Pictograms

GHS08,GHS05

Signal Word

Danger

Hazard Statements

H318,H351,H361fd

Precautionary Statements

P202 - P280 - P305 + P351 + P338 - P308 + P313 - P405 - P501

Hazard Classifications

Carc. 2 - Eye Dam. 1 - Repr. 2

WGK

WGK 3

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grade:
pharmaceutical primary standard

API family:
chloramphenicol

manufacturer/tradename:
EDQM

mp:
149-153 °C (lit.)

application(s):
pharmaceutical (small molecule)

format:
neat

SMILES string:
OC[C@@H](NC(=O)C(Cl)Cl)[C@H](O)c1ccc(cc1)[N+]([O-])=O

InChI:
1S/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9-/m1/s1

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WIIZWVCIJKGZOK-RKDXNWHRSA-N

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CC(=O)C1CC1

InChI:
1S/C5H8O/c1-4(6)5-2-3-5/h5H,2-3H2,1H3

InChI key:
HVCFCNAITDHQFX-UHFFFAOYSA-N

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Cl[H].Cl[H].NCCSSCCN

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1S/C4H12N2S2.2ClH/c5-1-3-7-8-4-2-6;;/h1-6H2;2*1H

InChI key:
YUFRRMZSSPQMOS-UHFFFAOYSA-N