Human Dermal Microvascular Endothelial Cells: CADMEC/HMVEC, neonatal

Description

• General description: Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details.CADMEC/HMVEC provide an excellent model system to study many aspects of endothelial function and disease, especially those related to the microvasculature and capillary systems. HMVEC/CADMEC have been shown to express vWF, CD36 and CD31, are able to uptake DiI-Ac-LDL and are positive for functional activity by cytokine-stimulated leukocyte adherence.Select HMVEC lots have been additionally tested to demonstrate stimulation-dependent angiogenesis and key endothelial cell signaling pathways (phosphorylation of VEGFR, Akt, MAPK, and expression of Tie2, eNOS, Axl and Etk/Bmx).
• Cell Line Origin: Skin
• Application: Endothelial vessel function, cell signaling, angiogenesis
• Components: Cell Basal Medium containing 10% FBS & 10% DMSO
• Preparation Note: 2nd passage, >500,000 cells in Cell Basal Medium containing 10% FBS & 10% DMSOCan be cultured at least 16 doublings
• Subculture Routine: Please refer to the CADMEC/HMVEC Culture Protocol.
• Disclaimer: RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.