M5060
E-4031
≥98% (HPLC), lyophilized powder
Manufacturer: Sigma Aldrich
CAS Number: 113559-13-0
Synonym(S): N-[4-[[1-[2-(6-Methyl-2-pyridinyl)ethyl]-4-piperidinyl]carbonyl]phenyl]methanesulfonamide dihydrochloride
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 0.1 MG | M5060-0.1-MG | In Stock | ₹ 21,314.43 |
| 0.5 MG | M5060-0.5-MG | In Stock | ₹ 74,811.58 |
| 1 MG | M5060-1-MG | In Stock | ₹ 1,41,504.40 |
M5060 - 0.1 MG
In Stock
Quantity
1
Base Price: ₹ 21,314.43
GST (18%): ₹ 3,836.597
Total Price: ₹ 25,151.027
Quality Level
100
Assay
≥98% (HPLC)
form
lyophilized powder
storage condition
desiccated
technique(s)
cell culture | embryo: suitable
color
white
solubility
H2O: soluble
storage temp.
−20°C
SMILES string
Cl.Cl.Cc1cccc(CCN2CCC(CC2)C(=O)c3ccc(NS(C)(=O)=O)cc3)n1
InChI
1S/C21H27N3O3S.2ClH/c1-16-4-3-5-19(22-16)12-15-24-13-10-18(11-14-24)21(25)17-6-8-20(9-7-17)23-28(2,26)27;;/h3-9,18,23H,10-15H2,1-2H3;2*1H
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Medchemexpress LLC HY-15551 10mg , E-4031 CAS:113559-13-0 Purity:>98% | Medchemexpress LLC | ₹ 12,148.50 | |
 | Sigma Aldrich Fine Chemicals Biosciences E-4031 >=98% (HPLC), lyophilized powder | 113559-13-0 | MFCD01754739 | 0.5MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 82,230.66 | |
| | eMolecules Ambeed / N-(4-(1-(2-(6-Methylpyridin-2-yl)ethyl)piperidine-4-carbonyl)phenyl)methanesulfonamide dihydrochloride / 5mg / 514322910 / A115118 / / 113559-13-0 / MFCD01754739 / 474.440 / C21H29Cl2N3O3S | eMolecules | ₹ 7,598.82 | |
 | Methanesulfonamide, N-[4-[[1-[2-(6-methyl-2-pyridinyl)ethyl]-4-piperidinyl]carbonyl]phenyl]-, hydrochloride (1:2) | Aaron Chemicals LLC | ₹ 4,183.00 - ₹ 26,344.00 | |
 | 113559-13-0 | E-4031 | A2B Chem | ₹ 2,047.00 - ₹ 82,058.00 |
Related Products
Description
- Application: E-4031 has been used as:human ether-a-go-go-related gene (hERG) blocker in human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)[1]IKr blocker in long QT syndrome (LQTS) induced pluripotent stem (iPSCs) embryoid bodies[2] IKr blocker in rat ventricular myocytes[3]
- Biochem/physiol Actions: E-4031 is a antiarrhythmic drug and belongs to the class III type. It is a methanesulfonanilide compound and is effective in treating arrhythmia and modulates ventricular fibrillation.[4] E-4031 mediates the prolongation of action potential duration (APD) in transgenic long-QT type 1 (LQT1) rabbits.[5] An isoleucine mutation in human ether-a-go-go-related gene (hERG) abolishes its interaction with E-4031.[6]
- Features and Benefits: This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Quality Level: 100
Assay: ≥98% (HPLC)
form: lyophilized powder
storage condition: desiccated
technique(s): cell culture | embryo: suitable
color: white
solubility: H2O: soluble
storage temp.: −20°C
SMILES string: Cl.Cl.Cc1cccc(CCN2CCC(CC2)C(=O)c3ccc(NS(C)(=O)=O)cc3)n1
InChI: 1S/C21H27N3O3S.2ClH/c1-16-4-3-5-19(22-16)12-15-24-13-10-18(11-14-24)21(25)17-6-8-20(9-7-17)23-28(2,26)27;;/h3-9,18,23H,10-15H2,1-2H3;2*1H
Quality Level:
100
Assay:
≥98% (HPLC)
form:
lyophilized powder
storage condition:
desiccated
technique(s):
cell culture | embryo: suitable
color:
white
solubility:
H2O: soluble
storage temp.:
−20°C
SMILES string:
Cl.Cl.Cc1cccc(CCN2CCC(CC2)C(=O)c3ccc(NS(C)(=O)=O)cc3)n1
InChI:
1S/C21H27N3O3S.2ClH/c1-16-4-3-5-19(22-16)12-15-24-13-10-18(11-14-24)21(25)17-6-8-20(9-7-17)23-28(2,26)27;;/h3-9,18,23H,10-15H2,1-2H3;2*1H
Quality Level: 200
Assay: __
form: buffered aqueous solution
storage condition: __
technique(s): __
color: __
solubility: __
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SMILES string: __
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Quality Level:
200
Assay:
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form:
buffered aqueous solution
storage condition:
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color:
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Quality Level: 100
Assay: >95% (SDS-PAGE)
form: lyophilized powder
storage condition: __
technique(s): __
color: __
solubility: __
storage temp.: −20°C
SMILES string: __
InChI: __
Quality Level:
100
Assay:
>95% (SDS-PAGE)
form:
lyophilized powder
storage condition:
__
technique(s):
__
color:
__
solubility:
__
storage temp.:
−20°C
SMILES string:
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Quality Level: 200
Assay: 99%
form: liquid
storage condition: __
technique(s): __
color: __
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SMILES string: __
InChI: __
Quality Level:
200
Assay:
99%
form:
liquid
storage condition:
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