P302-05

Porcine Pulmonary Artery Endothelial Cells: PPAEC (Cryovial)

Manufacturer: Sigma Aldrich

Select a Size

Pack Size SKU Availability Price
1 EACH P302-05-1-EACH In Stock ₹ 90,398.40

P302-05 - 1 EACH

₹ 90,398.40

In Stock

Quantity

1

Base Price: ₹ 90,398.40

GST (18%): ₹ 16,271.712

Total Price: ₹ 1,06,670.112

biological source

Porcine pulmonary artery (Normal healthy)

Quality Level

100

form

solid

packaging

pkg of 500,000 cells

manufacturer/tradename

Cell Applications, Inc

growth mode

Adherent

karyotype

2n = 38

morphology

Endothelial

technique(s)

cell culture | mammalian: suitable

relevant disease(s)

diabetes; cardiovascular diseases

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Description

  • General description: Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details.PPAEC have been used in a pioneer study of endothelial cell motility, where it was determined that asymmetric dimethylarginine (ADMA), an inhibitor of nitric oxide production and a cardiovascular risk factor, decreased PKG-mediated phosphorylation of VASP, leading to downregulation of Rac1 and induction of stress fibers and focal adhesions via RhoA/ROCK dependent mechanism, leading to decreased cell motility, and increase in endothelial permeability, thus linking vascular repair and function with NO production (Wojciak-Stothard, 2007, 2009). PPAEC were also used to assess endothelial adhesion to decellularized porcine arteries in order to develop grafts for human vascular repair (Xiong, 2013).
  • Cell Line Origin: Artery
  • Application: cardiovascular function, screening of drug candidates, angiogenesis, vasodilator function, transport of deoxygenated bloood from heart to lungs
  • Components: Porcine Endothelial Cell Growth Medium that contains 10% FBS and 10% DMSO
  • Preparation Note: 1st passage, >500,000 cells in Porcine Endothelial Cell Growth Medium that contains 10% FBS and 10% DMSOCan be cultured at least 16 doublings
  • Subculture Routine: Please refer to the PPAEC Culture Protocol.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Cell Applications, Inc

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Adherent

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diabetes; cardiovascular diseases

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