4830736

R&D Systems™ Cultrex Basement Membrane Extract, Type 3 (w/ Phenol Red)

Physiologically aligned with the in vivo solid tumors environment and is recommended for xenografts and other in vivo applications

Manufacturer: Fischer Scientific

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Content And Storage

Product is stable for a minimum of 3 months from date of shipment when stored at -20° C in a manual defrost freezer. For optimal stability, store at -80° C. Avoid freeze-thaw cycles.

Concentration

12 to 18 mg/mL

For Use With (Application)

Bioactivity

Source

Murine Engelbreth-Holm-Swarm (EHS) tumor.

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Description

  • Basement membranes are continuous sheets of specialized extracellular matrix that form an interface between endothelial, epithelial, muscle, or neuronal cells and their adjacent stroma
  • Basement membranes are degraded and regenerated during development and wound healing
  • They not only support cells and cell layers, but they also play an essential role in tissue organization that affects cell adhesion, migration, proliferation, and differentiation
  • Basement membranes provide major barriers to invasion by metastatic tumor cells
  • The major components of BME include laminin, collagen IV, entactin, and heparin sulfate proteoglycan BME can be used in a multiple applications, under a variety of cell culture conditions, for maintaining growth or promoting differentiation of primary endothelial, epithelial, smooth muscle and stem cells BME can also be utilized in cell attachment, neurite outgrowth, angiogenesis, in vitro cell invasion and in vivo tumorigenicity assays Higher tensile strength than standard BME RPMI1640 medium without phenol red Sterility tested Applications: solid tumors

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Content And Storage:
Product is stable for a minimum of 3 months from date of shipment when stored at -20° C in a manual defrost freezer. For optimal stability, store at -80° C. Avoid freeze-thaw cycles.

Concentration:
12 to 18 mg/mL

For Use With (Application):
Bioactivity

Source:
Murine Engelbreth-Holm-Swarm (EHS) tumor.

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