Corning™ Dulbecco's Modification of Eagle's Medium (DMEM) 1X1, Powder

Description

• Growth Promotion and Cytotoxicity Corning classical media products undergo a variety of tests to determine functionality and toxicity using growth-promotion analysis
• Product performance is measured by harvest-to-plant ratios or fold increase according to predetermined specifications
• Physiochemical Properties Liquid and powder classical media products are tested to determine pH and osmolality
• Classical media powders are also tested for residual moisture
• The pH and osmolality tests are performed according to specific procedures in which all equipment is calibrated using standards traceable to the National Institute of Standards and Technology
• Biological Tests Quality release testing of Corning liquid classical media products assures low levels of endotoxin, mycoplasma, and an absence of contamination
• Endotoxin: Classical media products are tested for bacterial endotoxin using the Limulus Amoebocyte Lysate (LAL) chromogenic assay
• For release, each lot of standard liquid classical media must have an endotoxin level of <0.25 EU/mL
• Classical media powder products must have an endotoxin level of <0.25 EU/mL when reconstituted to formula weight with low endotoxin water
• Sterility: All Corning liquid classical media products are tested for sterility
• Mycoplasma: Liquid classical media products are tested for mycoplasma using a large-volume method.