Fmoc-Cys(Trt)-OH
≥95.0% (sum of enantiomers, HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 103213-32-7
Synonym(S): N-(9-Fluorenylmethoxycarbonyl)-S-trityl-L-cysteine, Nα-Fmoc-S-trityl-L-cysteine
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 G | 47695-5-G | In Stock | ₹ 7,122.85 |
| 100 G | 47695-100-G | In Stock | ₹ 17,763.83 |
| 1 KG | 47695-1-KG | In Stock | ₹ 92,651.18 |
47695 - 5 G
In Stock
Quantity
1
Base Price: ₹ 7,122.85
GST (18%): ₹ 1,282.113
Total Price: ₹ 8,404.963
Quality Level
100
Assay
≥95.0% (sum of enantiomers, HPLC)
optical activity
[α]20/D +16.0±2°, c = 1% in THF
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
mp
170-173 °C (lit.)
application(s)
peptide synthesis
functional group
Fmoc
storage temp.
2-8°C
SMILES string
OC(=O)[C@H](CSC(c1ccccc1)(c2ccccc2)c3ccccc3)NC(=O)OCC4c5ccccc5-c6ccccc46
InChI
1S/C37H31NO4S/c39-35(40)34(38-36(41)42-24-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33)25-43-37(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28/h1-23,33-34H,24-25H2,(H,38,41)(H,39,40)/t34-/m0/s1
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Description
- General description: Fmoc-Cys(Trt)-OH is an amino acid commonly used in the Fmoc solid-phase peptide synthesis. [1]
- Application: Fmoc-Cys(Trt)-OH is an N-terminal protected cysteine derivative used in peptide synthesis. Some of the examples are:Synthesis of mono- and bi-functionalized platinum(IV) complexes to target angiogenic tumor vasculature.[2]Synthesis of proteins through native chemical ligation of peptide hydrazides as thioester surrogates via solid-phase synthesis.[3]Synthesis of glycoconjugates by conjugating reducing sugars to cysteine residues of peptides.[4]
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Quality Level: 100
Assay: ≥95.0% (sum of enantiomers, HPLC)
optical activity: [α]20/D +16.0±2°, c = 1% in THF
reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
mp: 170-173 °C (lit.)
application(s): peptide synthesis
functional group: Fmoc
storage temp.: 2-8°C
SMILES string: OC(=O)[C@H](CSC(c1ccccc1)(c2ccccc2)c3ccccc3)NC(=O)OCC4c5ccccc5-c6ccccc46
InChI: 1S/C37H31NO4S/c39-35(40)34(38-36(41)42-24-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33)25-43-37(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28/h1-23,33-34H,24-25H2,(H,38,41)(H,39,40)/t34-/m0/s1
Quality Level: 100
Assay: 97%
optical activity: [α]20/D +16°, c = 1 in methanol
reaction suitability: __
mp: 189 °C (dec.) (lit.)
application(s): __
functional group: __
storage temp.: __
SMILES string: Br.N[C@@H](CCBr)C(O)=O
InChI: 1S/C4H8BrNO2.BrH/c5-2-1-3(6)4(7)8;/h3H,1-2,6H2,(H,7,8);1H/t3-;/m0./s1
Quality Level: 100
Assay: 90%
optical activity: __
reaction suitability: __
mp: 247-252 °C (lit.)
application(s): __
functional group: __
storage temp.: __
SMILES string: Brc1ccc2NC(=O)C(=O)c2c1
InChI: 1S/C8H4BrNO2/c9-4-1-2-6-5(3-4)7(11)8(12)10-6/h1-3H,(H,10,11,12)
