H1637
cis-4-Hydroxy-L-proline
collagen synthesis inhibitor
Manufacturer: Sigma Aldrich
CAS Number: 618-27-9
Synonym(S): (2S,4S)-(−)-4-Hydroxy-2-pyrrolidinecarboxylic acid, CHP
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 50 MG | H1637-50-MG | In Stock | ₹ 7,620.80 |
| 250 MG | H1637-250-MG | In Stock | ₹ 20,697.40 |
| 1 G | H1637-1-G | In Stock | ₹ 68,673.80 |
H1637 - 50 MG
In Stock
Quantity
1
Base Price: ₹ 7,620.80
GST (18%): ₹ 1,371.744
Total Price: ₹ 8,992.544
Quality Level
100
Assay
≥98% (TLC)
form
powder
technique(s)
ligand binding assay: suitable
color
white to faint yellow
mp
257 °C (dec.) (lit.)
application(s)
peptide synthesis
SMILES string
O[C@@H]1CN[C@@H](C1)C(O)=O
InChI
1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4-/m0/s1
InChI key
PMMYEEVYMWASQN-IMJSIDKUSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Chem-Impex International, Inc. cis-L-4-Hydroxyproline | 618-27-9 | MFCD00064319 | 1G | Chem-Impex International, Inc. | ₹ 5,995.19 | |
 | cis-4-Hydroxy-L-proline | ChemScene | ₹ 427.80 - ₹ 84,191.04 |
Related Products
Description
- Application: cis-4-Hydroxy-L-proline (CHP) is a proline analog that inhibits collagen synthesis and has been used as an anticancer compound.[1] CHP blocked myotube formation and expression of sarcomeric myosin heavy chain in C2C12 murine skeletal muscle cells.[2] CHP inhibited proliferation of murine Panc02 pancreatic carcinoma cell line[3] and rat pancreatic carcinoma cell line DSL6A.[4]
- Biochem/physiol Actions: cis-4-Hydroxy-L-proline (CHP) and its derivatives may have anticancer activity. cis-4-Hydroxy-L-proline and other hydrosyl-L-prolines are important intermediates for chiral synthesis of potential drugs.
- Other Notes: Constituent of Amanita sp. peptide toxins but not of animal proteins like collagen.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
Show Difference
Quality Level: 100
Assay: ≥98% (TLC)
form: powder
technique(s): ligand binding assay: suitable
color: white to faint yellow
mp: 257 °C (dec.) (lit.)
application(s): peptide synthesis
SMILES string: O[C@@H]1CN[C@@H](C1)C(O)=O
InChI: 1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4-/m0/s1
InChI key: PMMYEEVYMWASQN-IMJSIDKUSA-N
Quality Level:
100
Assay:
≥98% (TLC)
form:
powder
technique(s):
ligand binding assay: suitable
color:
white to faint yellow
mp:
257 °C (dec.) (lit.)
application(s):
peptide synthesis
SMILES string:
O[C@@H]1CN[C@@H](C1)C(O)=O
InChI:
1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4-/m0/s1
InChI key:
PMMYEEVYMWASQN-IMJSIDKUSA-N
Quality Level: 200
Assay: ≥93% (HPLC)
form: ethanol solution
technique(s): __
color: __
mp: __
application(s): __
SMILES string: CCCCC[C@H](O)\C=C\C=C\C\C=C/CCCC(O)=O
InChI: 1S/C17H28O3/c1-2-3-10-13-16(18)14-11-8-6-4-5-7-9-12-15-17(19)20/h5-8,11,14,16,18H,2-4,9-10,12-13,15H2,1H3,(H,19,20)/b7-5-,8-6+,14-11+/t16-/m0/s1
InChI key: KUKJHGXXZWHSBG-WBGSEQOASA-N
Quality Level:
200
Assay:
≥93% (HPLC)
form:
ethanol solution
technique(s):
__
color:
__
mp:
__
application(s):
__
SMILES string:
CCCCC[C@H](O)\C=C\C=C\C\C=C/CCCC(O)=O
InChI:
1S/C17H28O3/c1-2-3-10-13-16(18)14-11-8-6-4-5-7-9-12-15-17(19)20/h5-8,11,14,16,18H,2-4,9-10,12-13,15H2,1H3,(H,19,20)/b7-5-,8-6+,14-11+/t16-/m0/s1
InChI key:
KUKJHGXXZWHSBG-WBGSEQOASA-N
Quality Level: 400
Assay: __
form: liquid
technique(s): cell culture | mammalian: suitable
color: __
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application(s): __
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Quality Level:
400
Assay:
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form:
liquid
technique(s):
cell culture | mammalian: suitable
color:
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application(s):
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SMILES string:
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InChI:
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Quality Level: 400
Assay: __
form: liquid
technique(s): cell culture | mammalian: suitable
color: __
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application(s): __
SMILES string: __
InChI: __
InChI key: __
Quality Level:
400
Assay:
__
form:
liquid
technique(s):
cell culture | mammalian: suitable
color:
__
mp:
__
application(s):
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SMILES string:
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InChI:
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