Description

• General description: 1-Acetylpyrene is a pyrene derivative. Its synthesis has been reported.[1] Its phytophysical properties have been studied using absolute fluorescence quantum yield measurement and time-dependent density functional theory (TD-DFT) calculations.[2] Its ability to interact with human cytochromes P450 2A13, 2A6, and 1B1 and enzyme inhibition has been reported.[3] Its function as an environment-sensitive fluorophore has been investigated.[4]
• Application: 1-Acetylpyrene is suitable for use in a comparative study on the photoinitiating efficiency of pyrene, 1-acetylpyrene and 1-(bromoacetyl)pyrene for copolymerization of styrene with acrylonitrile.[5] It may be used in the following studies:As a starting material in the synthesis of ethynlypyrene. 1-(1-chlorovinyl)pyrene was also isolated during this reaction.[6] As a starting material in the synthesis of substituted pyrene derivatives incorporated heterocyclic and sugar moieties.[7]Synthesis of (E)-pyrene oxime ester conjugates of carboxylic acids.[8]Synthesis of tertiary alcohols based on 1-acetylpyrene.[9]Synthesis of (E)-N-[1-(pyren-1-yl)ethylidene]chrysene-2-amine.[10] Synthesis of 3,3-di(methylsulfanyl)-1-(1-pyrenyl)-2-propen-1-one.[11]