808512

γ-[(Propargyl)-imido]-ATP sodium salt

Manufacturer: Sigma Aldrich

Synonym(S): Adenosine-5’-[γ-(propargyl)-imido]triphosphate sodium salt

Select a Size

Pack Size SKU Availability Price
1 MG 808512-1-MG In Stock ₹ 16,118.43

808512 - 1 MG

₹ 16,118.43

In Stock

Quantity

1

Base Price: ₹ 16,118.43

GST (18%): ₹ 2,901.317

Total Price: ₹ 19,019.747

Assay

≥95% (HPLC)

Quality Level

200

form

solid

reaction suitability

reaction type: click chemistry

solubility

10 mM Tris-HCl, pH 7.5: soluble

shipped in

wet ice

storage temp.

−20°C

SMILES string

NC1=NC=NC2=C1N=CN2[C@H]3O[C@H](COP(OP(O)(OP(O)(NCC#C)=O)=O)(O)=O)[C@@H](O)[C@H]3O

InChI

1S/C13H19N6O12P3/c1-2-3-18-32(22,23)30-34(26,27)31-33(24,25)28-4-7-9(20)10(21)13(29-7)19-6-17-8-11(14)15-5-16-12(8)19/h1,5-7,9-10,13,20-21H,3-4H2,(H,24,25)(H,26,27)(H2,14,15,16)(H2,18,22,23)/t7-,9-,10-,13?/m1/s1

InChI key

PIPOEUYSJJTELD-RJNFYWFKSA-N

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Description

  • Application: Lee, et al,.[1] reported a non-radioactive version of in vitro phosphorylation where γ-[(Propargyl)-imido]-ATP (compound 1)[1] was successfully used instead of γ-32P-modified ATP to phosphorylate GST-tagged recombinant p27kip1 with protein kinase cdk2. The phosphorylated, alkyne-modified protein substrate can be labeled with azides of biotin or fluorescent dyes using Cu(I)-catalyzed click chemistry.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Sigma Aldrich

808512

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Assay:
≥95% (HPLC)

Quality Level:
200

form:
solid

reaction suitability:
reaction type: click chemistry

solubility:
10 mM Tris-HCl, pH 7.5: soluble

shipped in:
wet ice

storage temp.:
−20°C

SMILES string:
NC1=NC=NC2=C1N=CN2[C@H]3O[C@H](COP(OP(O)(OP(O)(NCC#C)=O)=O)(O)=O)[C@@H](O)[C@H]3O

InChI:
1S/C13H19N6O12P3/c1-2-3-18-32(22,23)30-34(26,27)31-33(24,25)28-4-7-9(20)10(21)13(29-7)19-6-17-8-11(14)15-5-16-12(8)19/h1,5-7,9-10,13,20-21H,3-4H2,(H,24,25)(H,26,27)(H2,14,15,16)(H2,18,22,23)/t7-,9-,10-,13?/m1/s1

InChI key:
PIPOEUYSJJTELD-RJNFYWFKSA-N

Img

Sigma Aldrich

808520

--


Assay:
≥95% (HPLC)

Quality Level:
200

form:
powder

reaction suitability:
reaction type: click chemistry

solubility:
10 mM Tris-HCl, pH 7.5: soluble

shipped in:
wet ice

storage temp.:
−20°C

SMILES string:
O[C@@H]([C@H]1O)[C@@H](COP(O)(OP(O)(OP(NCCCCCCN=[N+]=[N-])(O)=O)=O)=O)O[C@@H]1N2C=NC3=C2N=CN=C3N

InChI:
1S/C16H28N9O12P3/c17-14-11-15(20-8-19-14)25(9-21-11)16-13(27)12(26)10(35-16)7-34-39(30,31)37-40(32,33)36-38(28,29)23-6-4-2-1-3-5-22-24-18/h8-10,12-13,16,26-27H,1-7H2,(H,30,31)(H,32,33)(H2,17,19,20)(H2,23,28,29)/t10-,12-,13-,16?/m1/s1

InChI key:
FZLLGYSKHRTLRX-AARXTDBFSA-N

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