LightOx™21

Description

• Application: Fluorescence microscopy, fluorescent retinoid binding assay, fluorescence spectroscopy.
• Biochem/physiol Actions: Strong ligand for retinoic acid receptor proteins
• Features and Benefits: LightOx21 is a synthetic analogue of all-trans-retinoic acid (ATRA), that exhibits solvatochromatic fluorescence emission when excited with UV or 405 nm light. The compound is a strong ligand for the retinoic acid receptor proteins (RARs) and related cellular retinoic acid binding proteins (CRABPI/II) and can, therefore, be used as a replacement for ATRA in cellular assays involving retinoid signaling processes. LightOx21 can be utilised to study retinoid behaviour using fluorescence microscopy, employed in a competitive fluorometric ligand-binding assay for direct determination of the strength of binding of non-fluorescent retinoids to a protein target, and as a fluorophore in fluorescence spectroscopy.Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)
• Other Notes: Chemical Equivalency 1ea=1mg
• Legal Information: LightOx is a trademark of LightOx Ltd.