QBD10374
SPDP-dPEG®4-NHS ester
Manufacturer: Sigma Aldrich
CAS Number: 1334177-95-5
Synonym(S): 2,5-Dioxo-1-pyrrolidinyl 17-oxo-19-(2-pyridinyldithio)-4,7,10,13-tetraoxa-16-azanonadecanoate
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 MG | QBD10374-100-MG | In Stock | ₹ 22,234.55 |
QBD10374 - 100 MG
In Stock
Quantity
1
Base Price: ₹ 22,234.55
GST (18%): ₹ 4,002.219
Total Price: ₹ 26,236.769
Assay
>90%
form
solid or viscous liquid
reaction suitability
reactivity: thiol reactivereagent type: cross-linking reagentreactivity: amine reactive
functional group
NHS ester
polymer architecture
shape: linearfunctionality: heterobifunctional
shipped in
ambient
storage temp.
−20°C
SMILES string
O=C(NCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O)CCSSC2=NC=CC=C2
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Sigma Aldrich Fine Chemicals Biosciences SPDP-dPEG(R)4-NHS ester | Purity: >90% | Mol Wt: 559.65 | 1334177-95-5 | MFCD13185001 | 100MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 34,902.49 | |
 | eMolecules 2,5-dioxopyrrolidin-1-yl 3-oxo-1-(pyridin-2-yldisulfanyl)-7,10,13,16-tetraoxa-4-azanonadecan-19-oate | 1334177-95-5 | MFCD13185001 | 250mg | eMolecules | ₹ 56,559.44 | |
 | SPDP-PEG4-NHS ester | ChemScene | ₹ 16,085.28 | |
 | 1334177-95-5 | Opss-peg(4)-nhs | A2B Chem | ₹ 9,240.48 - ₹ 18,480.96 |
Related Products
Description
- Features and Benefits: SPDP-dPEG®4-NHS ester has an amine-reactive N-hydroxysuccinimide (NHS) ester at one end and a sulfhydryl-reactive 2-pyridyldithiol group at the opposite end. This has a single molecular weight PEG spacer arm, which confers greater water solubility to the crosslinker and linked proteins compared to crosslinkers having only hydrocarbon spacers. Protein aggregation and precipitation also are greatly reduced with SPDP-dPEG crosslinkers compared to crosslinkers that have only hydrocarbon spacers. dPEG spacer of specific length (23.1 Å) provides precise distance control between the SPDP moiety and the target molecule. Pyridyldithiol reagents produce disulfide-containing linkages that can be cleaved with reducing agents such as dithiothreitol (DTT). Crosslinking experiments with SPDP reagents are not limited to those involving proteins. Any of a variety of molecules with primary amines and sulfhydryl groups can be modified or crosslinked using SPDP reagents.
- Legal Information: Products Protected under U.S. Patents # 7,888,536 B2
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
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Assay: >90%
form: solid or viscous liquid
reaction suitability: reactivity: thiol reactivereagent type: cross-linking reagentreactivity: amine reactive
functional group: NHS ester
polymer architecture: shape: linearfunctionality: heterobifunctional
shipped in: ambient
storage temp.: −20°C
SMILES string: O=C(NCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O)CCSSC2=NC=CC=C2
Assay:
>90%
form:
solid or viscous liquid
reaction suitability:
reactivity: thiol reactivereagent type: cross-linking reagentreactivity: amine reactive
functional group:
NHS ester
polymer architecture:
shape: linearfunctionality: heterobifunctional
shipped in:
ambient
storage temp.:
−20°C
SMILES string:
O=C(NCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O)CCSSC2=NC=CC=C2
Assay: >90%
form: solid or viscous liquid
reaction suitability: reactivity: thiol reactivereagent type: cross-linking reagentreactivity: amine reactive
functional group: NHS ester
polymer architecture: shape: linearfunctionality: heterobifunctional
shipped in: ambient
storage temp.: −20°C
SMILES string: O=C(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O)CCSSC2=NC=CC=C2
Assay:
>90%
form:
solid or viscous liquid
reaction suitability:
reactivity: thiol reactivereagent type: cross-linking reagentreactivity: amine reactive
functional group:
NHS ester
polymer architecture:
shape: linearfunctionality: heterobifunctional
shipped in:
ambient
storage temp.:
−20°C
SMILES string:
O=C(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O)CCSSC2=NC=CC=C2
Assay: >90%
form: solid or viscous liquid
reaction suitability: reactivity: thiol reactivereagent type: cross-linking reagentreactivity: amine reactive
functional group: __
polymer architecture: shape: linearfunctionality: heterobifunctional
shipped in: ambient
storage temp.: −20°C
SMILES string: O=C(CCSSC1=NC=CC=C1)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O
Assay:
>90%
form:
solid or viscous liquid
reaction suitability:
reactivity: thiol reactivereagent type: cross-linking reagentreactivity: amine reactive
functional group:
__
polymer architecture:
shape: linearfunctionality: heterobifunctional
shipped in:
ambient
storage temp.:
−20°C
SMILES string:
O=C(CCSSC1=NC=CC=C1)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O
Assay: >90%
form: solid or viscous liquid
reaction suitability: reactivity: thiol reactivereagent type: cross-linking reagentreactivity: amine reactive
functional group: __
polymer architecture: shape: linearfunctionality: heterobifunctional
shipped in: ambient
storage temp.: −20°C
SMILES string: O=C(CCSSC1=NC=CC=C1)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O
Assay:
>90%
form:
solid or viscous liquid
reaction suitability:
reactivity: thiol reactivereagent type: cross-linking reagentreactivity: amine reactive
functional group:
__
polymer architecture:
shape: linearfunctionality: heterobifunctional
shipped in:
ambient
storage temp.:
−20°C
SMILES string:
O=C(CCSSC1=NC=CC=C1)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O