561037

3,4-Difluorophenylmagnesium bromide solution

0.5 M in THF

Manufacturer: Sigma Aldrich

CAS Number: 90897-92-0

Select a Size

Pack Size SKU Availability Price
50 ML 561037-50-ML In Stock ₹ 20,513.38

561037 - 50 ML

₹ 20,513.38

In Stock

Quantity

1

Base Price: ₹ 20,513.38

GST (18%): ₹ 3,692.408

Total Price: ₹ 24,205.788

reaction suitability

reaction type: Grignard Reaction

Quality Level

100

concentration

0.5 M in THF

bp

65 °C

density

0.965 g/mL at 25 °C

storage temp.

2-8°C

SMILES string

Fc1ccc([Mg]Br)cc1F

InChI

1S/C6H3F2.BrH.Mg/c7-5-3-1-2-4-6(5)8;;/h1,3-4H;1H;/q;;+1/p-1

InChI key

WZHAVYGMKGPNFN-UHFFFAOYSA-M

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Description

  • Application: 3,4-Difluorophenylmagnesium bromide can be used:To prepare 3,4-difluorophenylboronic acid, a key building block employed in the synthesis of norepinephrine transporter selective molecules.[1]In the synthesis of trimethoxybenzophenone derived tubulin polymerization inhibitors.[2]In one of the key synthetic steps for the preparation of diarylketoxime derivatives as potent MCH-1R antagonists.[3]In the synthesis of biologically important hydroxybupropion analogs useful in smoking cessation.[4]
  • Legal Information: Product of Rieke Metals, Inc. Rieke is a registered trademark of Rieke Metals, Inc.

SAFETY INFORMATION

Pictograms

GHS02,GHS08,GHS07

Signal Word

Danger

Hazard Statements

H225,H302,H319,H335,H351

Precautionary Statements

P210 - P280 - P301 + P312 + P330 - P305 + P351 + P338 - P370 + P378 - P403 + P235

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Respiratory system

Supplementary Hazards

EUH019

WGK

WGK 3

Flash Point(F)

1.0 °F

Flash Point(C)

-17.2 °C

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561037

0.5 M in THF...


reaction suitability:
reaction type: Grignard Reaction

Quality Level:
100

concentration:
0.5 M in THF

bp:
65 °C

density:
0.965 g/mL at 25 °C

storage temp.:
2-8°C

SMILES string:
Fc1ccc([Mg]Br)cc1F

InChI:
1S/C6H3F2.BrH.Mg/c7-5-3-1-2-4-6(5)8;;/h1,3-4H;1H;/q;;+1/p-1

InChI key:
WZHAVYGMKGPNFN-UHFFFAOYSA-M

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reaction type: Grignard Reaction

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100

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bp:
65 °C

density:
0.951 g/mL at 25 °C

storage temp.:
2-8°C

SMILES string:
CN(C)c1ccc([Mg]Br)cc1

InChI:
1S/C8H10N.BrH.Mg/c1-9(2)8-6-4-3-5-7-8;;/h4-7H,1-2H3;1H;/q;;+1/p-1

InChI key:
OWWWKAXERYRWAU-UHFFFAOYSA-M

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SMILES string:
Br[Ni]Br

InChI:
1S/2BrH.Ni/h2*1H;/q;;+2/p-2

InChI key:
IPLJNQFXJUCRNH-UHFFFAOYSA-L