Description

• General description: We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is a fluorine donor also called Selectfluor and has been enhanced for catalysis. Find details here.
• Application: 1-Chloromethyl-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate) is an electrophilic fluorinating reagent used for greener fluorination of acetoacetamides in PEG-400.Catalyst-free and highly selective electrophilic mono-fluorination of acetoacetamides: facile and efficient preparation of 2-fluoroacetoacetamides in PEG-400It can be used:As a highly effective and versatile source of electrophilic fluorine.[1]As a fluorinating reagent that effects oxidative ring opening of 2,5-diarylfurans to cis-1,4-enediones.[2] For direct fluorination of silyl ketene acetals leading to the formation of α-fluoro-α-arylcarboxylic acids.[3]As an electrophilic fluorinating reagent used. e.g. in the preparation of fluorinated acylsilanes.[4]
• Other Notes: First application of ionic liquids in electrophilic fluorination of arenes; Selectfluor (F-TEDA-BF4) for “green” fluorination.
• Citation: A review.[5]