C6506

4-Chloro-DL-phenylalanine

Manufacturer: Sigma Aldrich

CAS Number: 7424-00-2

Synonym(S): PCP, PCPA

Select a Size

Pack Size SKU Availability Price
5 G C6506-5-G In Stock ₹ 13,899.30
25 G C6506-25-G In Stock ₹ 52,306.40

C6506 - 5 G

₹ 13,899.30

In Stock

Quantity

1

Base Price: ₹ 13,899.30

GST (18%): ₹ 2,501.874

Total Price: ₹ 16,401.174

form

solid

Quality Level

100

greener alternative product score

old score: 2new score: 1Find out more about DOZN™ Scoring

greener alternative product characteristics

Less Hazardous Chemical SynthesesDesigning Safer ChemicalsDesign for Energy EfficiencyLearn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

mp

>240 °C (dec.) (lit.)

greener alternative category

, Re-engineered

storage temp.

room temp

SMILES string

NC(Cc1ccc(Cl)cc1)C(O)=O

InChI

1S/C9H10ClNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)

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Description

  • General description: We are committed to bringing you Greener Alternative Products, which adhere to one of the four categories of Greener Alternatives . This product belongs to category of Re-engineered products, showing key improvements in Green Chemistry Principles "Less Hazardous Chemical Syntheses", "Designing Safer Chemicals" and "Design for Energy Efficiency". Click here to view its DOZN scorecard.
  • Application: 4-Chloro-DL-phenylalanine has been used:as tryptophan hydroxylase 1 (TPH1) inhibitor to treat kras+ male zebrafish[1]to induce insomnia in rat models[2]used to treat embryos to examine its effect on serotonin[3]for the selection of Enterococcus faecalis transformants with pESentA32 plasmid[4]to feed flies to explore serotonin effect[5]
  • Biochem/physiol Actions: 4-Chloro-DL-phenylalanine (PCPA) is an inhibitor of 5-hydroxytrytamine (5-HT) synthesis. It helps to improve the inflammation of lung tissue and remodeling pulmonary artery. PCPA can reduce the expression of tryptophan hydroxylase 1 (TPH1), matrix metalloproteinase (MMP) and pro-inflammatory factors.[6]

SAFETY INFORMATION

Pictograms

GHS06

Signal Word

Danger

Hazard Statements

H301,H317

Precautionary Statements

P280 - P301 + P310 + P330 - P302 + P352

Hazard Classifications

Acute Tox. 3 Oral - Skin Sens. 1

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves