Description

• Application: Development and validation of an HPLC method for the determination of vancomycin in human plasma and its comparison with an immunoassay (PETINIA).: This study developed and validated an HPLC method using 70% perchloric acid for the determination of vancomycin in human plasma, highlighting its application in analytical chemistry for therapeutic drug monitoring (Usman and Hempel, 2016).Determination of sunscreen agents in cosmetic products by reversed-phase high performance liquid chromatography.: The research utilized 70% perchloric acid in the sample preparation process, demonstrating its efficacy in the analysis of cosmetic products for regulatory and quality control purposes (Yao et al., 1998).Colorimetric determination of hydroxyurea in human serum using high-performance liquid chromatography.: This article describes a colorimetric method involving 70% perchloric acid for sample preparation, which is crucial in clinical chemistry for monitoring hydroxyurea levels in patients (Manouilov et al., 1998).Application of biological samples treated by wet-digested mineralization to cation-exchange high-performance liquid chromatography with post-column reaction by 4-(2-pyridylazo)-resorcinol.: This study details the use of 70% perchloric acid in the mineralization of biological samples, essential for accurate trace metal analysis in biological research (Sudo et al., 1991).Colorimetric micromethods for glutaraldehyde determination by means of phenol and sulfuric acid or phenol and perchloric acid.: The research presents a micromethod utilizing 70% perchloric acid for the colorimetric determination of glutaraldehyde, applicable in biochemical and industrial laboratories for safety and quality assessments (Boratynski and Zal, 1990).
• Analysis Note: Assay (acidimetric): 70.0 - 72.0 %Color: ≤ 10 HazenChlorate (ClO₃): ≤ 10 ppmChloride (Cl): ≤ 3 ppmFree chlorine: ≤ 0.5 ppmPhosphate and Silicate (as SiO₂): ≤ 5 ppmSulfate (SO₄): ≤ 10 ppmTotal nitrogen (N): ≤ 10 ppmHeavy metals (as Pb): ≤ 1 ppmAg (Silver): ≤ 0.1 ppmAl (Aluminium): ≤ 0.05 ppmAs (Arsenic): ≤ 0.05 ppmBa (Barium): ≤ 0.02 ppmBe (Beryllium): ≤ 0.02 ppmBi (Bismuth): ≤ 0.1 ppmCa (Calcium): ≤ 0.5 ppmCd (Cadmium): ≤ 0.05 ppmCo (Cobalt): ≤ 0.05 ppmCu (Copper): ≤ 0.1 ppmFe (Iron): ≤ 1.0 ppmGe (Germanium): ≤ 0.05 ppmHg (Mercury): ≤ 0.005 ppmK (Potassium): ≤ 0.1 ppmLi (Lithium): ≤ 0.02 ppmMg (Magnesium): ≤ 0.5 ppmMn (Manganese): ≤ 0.02 ppmMo (Molybdenum): ≤ 0.05 ppmNa (Sodium): ≤ 0.5 ppmNi (Nickel): ≤ 0.1 ppmPb (Lead): ≤ 0.05 ppmSr (Strontium): ≤ 0.02 ppmTi (Titanium): ≤ 0.1 ppmTl (Thallium): ≤ 0.05 ppmV (Vanadium): ≤ 0.05 ppmZn (Zinc): ≤ 0.1 ppmZr (Zirconium): ≤ 0.1 ppmResidue on ignition (as sulfate): ≤ 30 ppmIdentity: passes testDensity (d 20/20): approx. 1.7 Conform to ACS, ISO, Reag.Ph Eur.
• Legal Information: EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany