MilliporeSigma™ Supelco™ CHIRALPAK™ CBH HPLC Column, 5 μm Particle Size

Description

• CHIRALPAK™ CBH phase has cellobiohydrolase as the chiral selector immobilized on spherical 5 μm silica particles
• Used in reversed-phase mode, retention and enantioselectivity is regulated by changes of pH, buffer concentration and organic modifier
• The mobile phases are mixtures of phosphate or acetate buffers and organic solvents such as 2-propanol or acetonitrile
• The column is preferably used for the separation of enantiomers of basic drugs, particularly compounds containing one or more nitrogen atoms along with one or more hydrogen-bonding groups (alcohol, phenol, carbonyl, amide, ether, ester, etc.)
• Features: Direct reversed phase resolution of chiral molecules
• Stable with a variety of organic modifiers
• Available in analytical and semi-preparative sizes.