Cytiva Sepharose™ Fast Flow Cation Exchange Media

Description

• Used for preparative protein separations in both research and industrial applications
• Cytiva CM Sepharose™ Fast Flow Cation Exchange Media is composed of crosslinked 6% agarose beads, with carboxymethyl (CM) weak cation exchange groups
• Hydrophilic nature of base matrix ensures low levels of non-specific binding leading to low levels of host cell-derived impurities in the elution pool Composed of crosslinked 6% agarose beads Reproducible Part of Sepharose Fast Flow ion exchange platform High chemical stability, allowing well proven cleaning-in-place (CIP) and sanitization protocols Available in range of pre-packed process development tools SP Sepharose: Ligand: Sulphopropyl Ion Exchanger Type: Strong cation exchanger Ionic Capacity: 0.18 to 0.25mmol H + /mL medium Binding capacity: 70mg ribonuclease A/mL medium CM Sepharose: Ligand: Carboxymethyl Ion Exchanger Type: Weak cation exchanger Ionic Capacity: 0.09 to 0.13mmol Hl + /mL medium Binding capacity: 50mg ribonuclease A/mL medium Used extensively for capture and intermediate purification of wide range of approved biopharmaceuticals