21-505-0

Tocris Bioscience™ nTZDpa

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 21-505-0-Each-of-1 In Stock ₹ 94,030.44

21-505-0 - Each of 1

₹ 94,030.44

In Stock

Quantity

1

Base Price: ₹ 94,030.44

GST (18%): ₹ 16,925.479

Total Price: ₹ 1,10,955.919

Purity

>98%

Product Type

nTZDpa

Inhibitors

nTZDpa

Quantity

50 mg

Molecular Weight (g/mol)

428.33

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Description

  • Potent, selective non-thiazolidinedione PPARγ partial agonist (EC50 = 57 nM); produces ∽25% maximum efficacy
  • Antagonizes full agonist activity by ∽60% (IC50 ∽ 285 nM)
  • Displays no activity at PPARα or PPARδ receptors
  • Produces altered receptor conformation, and regulates adipocyte development and gene expression, in a differential manner to full PPARγ agonists
  • Modulates metabolism and insulin sensitivity without causing cardiac hypertrophy in mice in vivo .

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