35-715-0R

Tocris Bioscience™ SB 657510

Manufacturer: Tocris Bioscience™

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Purity

>98%

Product Type

SB 657510

Inhibitors

SB 657510

Quantity

50 mg

Molecular Weight (g/mol)

505.81

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Description

  • Selective urotensin-II (UT) receptor antagonist (K i values are 61, 17, 30, 65 and 56 nM at human, monkey, cat, rat and mouse receptors respectively)
  • Inhibits U-II-induced intracellular Ca 2+ mobilization (IC 50 = 180 nM) and antagonizes the contractile action of U-II in isolated mammalian arteries and aortae (EC 50 = 50 - 189 nM).

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