36-311-0R

Tocris Bioscience™ FK 506

Manufacturer: Tocris Bioscience™

Select a Size

Pack Size SKU Availability Price
Each of 1 36-311-0R-Each-of-1 In Stock ₹ 21,475.56

36-311-0R - Each of 1

₹ 21,475.56

In Stock

Quantity

1

Base Price: ₹ 21,475.56

GST (18%): ₹ 3,865.601

Total Price: ₹ 25,341.161

Purity

>99%

Quantity

10 mg

Molecular Weight (g/mol)

804.02

Gene Alias

Tacrolimus, Fujimycin

Product Type

FK 506

Inhibitors

FK 506

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Description

  • FK 506 is a potent calcineurin (protein phosphatase 2B) inhibitor that requires FK 506-binding protein 12 (FKBP12) for activity (IC50 = 3 nM)
  • Inhibits secretion of IL-1, IL-2 (IC50 = 1 nM), IL-3, IL-4, IL-6 (IC50 = 35 nM), GM-CSF, TNFα (IC50 = 10 nM), IFNγ and Myc from activated T cells in vitro
  • Exhibits potent immunosuppressive, neuroprotective and anticonvulsant activity in vivo
  • Identified as targeting human host cell proteins that interact with SARS-CoV-2
  • Analog also available.

Compare Similar Items

Show Difference

Img

Tocris Bioscience™

36-311-0R

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Purity:
>99%

Quantity:
10 mg

Molecular Weight (g/mol):
804.02

Gene Alias:
Tacrolimus, Fujimycin

Product Type:
FK 506

Inhibitors:
FK 506

Img

Fischer Scientific

36-311-7180

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Purity:
__

Quantity:
25 μg

Molecular Weight (g/mol):
__

Gene Alias:
belly-spot; Bs; CD117; ckit; C-Kit; c-KIT gene1; c-kit protein; c-kit proto-oncogene protein; c-kit receptor; c-kit receptor tyrosine kinase; dominant spotting; Dominant white spotting; Fdc; Gsfsco1; Gsfsco5; Gsfsow3; KIT; kit oncogene; KIT proto-oncogene receptor tyrosine kinase; KIT proto-oncogene, receptor tyrosine kinase; mast cell growth factor receptor; mast/stem cell growth factor receptor; mast/stem cell growth factor receptor Kit; MGF; p145 c-kit; PBT; Piebald trait protein; protein kinase; proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; receptor tyrosine kinase c-kit; receptor tyrosine kinase type III; SCFR; SCO1; SCO5; Sl; soluble KIT variant 1; SOW3; spotted sterile male; Ssm; Steel Factor Receptor; Tr-kit; tyrosine kinase receptor; tyrosine kinase receptor c-KIT; tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; W

Product Type:
__

Inhibitors:
__

Img

Fischer Scientific

36-311-7182

--


Purity:
__

Quantity:
100 μg

Molecular Weight (g/mol):
__

Gene Alias:
belly-spot; Bs; CD117; ckit; C-Kit; c-KIT gene1; c-kit protein; c-kit proto-oncogene protein; c-kit receptor; c-kit receptor tyrosine kinase; dominant spotting; Dominant white spotting; Fdc; Gsfsco1; Gsfsco5; Gsfsow3; KIT; kit oncogene; KIT proto-oncogene receptor tyrosine kinase; KIT proto-oncogene, receptor tyrosine kinase; mast cell growth factor receptor; mast/stem cell growth factor receptor; mast/stem cell growth factor receptor Kit; MGF; p145 c-kit; PBT; Piebald trait protein; protein kinase; proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; receptor tyrosine kinase c-kit; receptor tyrosine kinase type III; SCFR; SCO1; SCO5; Sl; soluble KIT variant 1; SOW3; spotted sterile male; Ssm; Steel Factor Receptor; Tr-kit; tyrosine kinase receptor; tyrosine kinase receptor c-KIT; tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; W

Product Type:
__

Inhibitors:
__

Img

Fischer Scientific

36-312-3941

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Purity:
__

Quantity:
25 Tests

Molecular Weight (g/mol):
__

Gene Alias:
CD123; CD123 antigen; CDw123; Cyrl; cytokine receptor-like protein CYRL; hIL-3Ra; Il-3 alpha subunit; IL-3 receptor alpha chain; IL-3 receptor alpha SP2 isoform; IL-3 receptor subunit alpha; IL3R; IL-3R subunit alpha; Il3ra; IL-3RA; IL-3R-alpha; IL3RAY; IL3RX; IL3RY; interleukin 3 receptor subunit alpha; interleukin 3 receptor, alpha; interleukin 3 receptor, alpha (low affinity); interleukin 3 receptor, alpha chain; interleukin-3 receptor class II alpha chain; Interleukin-3 receptor subunit alpha; Sut-1

Product Type:
__

Inhibitors:
__