46-941-0

Tocris Bioscience™ Ro 5-3335

Manufacturer: Tocris Bioscience™

Select a Size

Pack Size SKU Availability Price
Each of 1 46-941-0-Each-of-1 In Stock ₹ 30,972.72

46-941-0 - Each of 1

₹ 30,972.72

In Stock

Quantity

1

Base Price: ₹ 30,972.72

GST (18%): ₹ 5,575.09

Total Price: ₹ 36,547.81

Purity

>98%

Quantity

10 mg

Molecular Weight (g/mol)

259.69

Gene Alias

CBFβ-Runx1 inhibitor II

Product Type

Ro 5-3335

Inhibitors

Ro 5-3335

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Description

  • Ro 5-3335 is a core binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins (IC50 = 1.1 μM)
  • Represses RUNX1/CBFβ-dependent transactivation in reporter assays and inhibits transcriptional regulation by RUNX1 and CBFβ
  • Reduces leukemia burden in a mouse model
  • Attenuates RUNX1-dependent hematopoiesis in zebrafish embryos
  • Also a Tat antagonist; inhibits HIV-1 replication in vitro .

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Show Difference

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Tocris Bioscience™

46-941-0

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Purity:
>98%

Quantity:
10 mg

Molecular Weight (g/mol):
259.69

Gene Alias:
CBFβ-Runx1 inhibitor II

Product Type:
Ro 5-3335

Inhibitors:
Ro 5-3335

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Fischer Scientific

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Purity:
__

Quantity:
25 Tests

Molecular Weight (g/mol):
__

Gene Alias:
2F1; 2F1-Ag; CLEC15A; C-type lectin domain family 15 member A; C-type lectin domain family 15, member A; ITIM-containing receptor MAFA-L; killer cell lectin like receptor G1; killer cell lectin-like receptor subfamily G member 1; killer cell lectin-like receptor subfamily G, member 1; Klrg1; Mafa; MAFA-2F1; MAFAL; MAFA-L; MAFA-LIKE; MAFA-like receptor; Mast cell function-associated antigen; mast cell function-associated antigen (ITIM-containing); mast cell function-associated antigen 2F1; natural killer cell receptor

Product Type:
Antibody

Inhibitors:
__

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Thermo Scientific™

46-960

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Purity:
__

Quantity:
__

Molecular Weight (g/mol):
__

Gene Alias:
__

Product Type:
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Inhibitors:
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Invitrogen

46-971-842

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Purity:
__

Quantity:
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Molecular Weight (g/mol):
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Gene Alias:
2610315D21Rik; AI327068; angiopoietin-like factor CDT6; FK506 binding protein 12-rapamycin associated protein 1; FK506 binding protein 12-rapamycin associated protein 2; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; FKBP12-rapamycin complex-associated protein 1; FKBP-rapamycin associated protein; FKBP-rapamycin associated protein (FRAP); FKBP-rapamycin-associated protein FRAP; flat; FRAP; FRAP1; FRAP2; Mammalian target of rapamycin; mechanistic target of rapamycin; mechanistic target of rapamycin (serine/threonine kinase); mechanistic target of rapamycin kinase; Mtor; m-TOR; mTORC1; Raft1; Rapamycin and FKBP12 target 1; rapamycin and FKBP12 target-1 protein; rapamycin associated protein FRAP2; rapamycin target protein 1; RAPT1; serine/threonine-protein kinase mTOR; SKS

Product Type:
Antibody

Inhibitors:
__