507550R

Tocris Bioscience™ Harmine

Manufacturer: Tocris Bioscience™

Select a Size

Pack Size SKU Availability Price
Each of 1 507550R-Each-of-1 In Stock ₹ 8,119.64

507550R - Each of 1

₹ 8,119.64

In Stock

Quantity

1

Base Price: ₹ 8,119.64

GST (18%): ₹ 1,461.535

Total Price: ₹ 9,581.175

Purity

>98%

Product Type

Harmine

Inhibitors

Harmine

Quantity

50 mg

Molecular Weight (g/mol)

212.25

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Description

  • Harmine is a potent and selective inhibitor of DYRK1A (IC50 values are 80, 800 and 900 nM for DYRK1A, DYRK3 and DYRK2 respectively)
  • Inhibits DYRK1A-mediated tau phosphorylation and regulates PPARγ expression
  • Harmine also induces pancreatic β cell proliferation and exhibits antidiabetic activity
  • Orally bioavailable
  • Harmine has high affinity (Kd = 100 nM) for the yjdF aptamer
  • The riboswitch function of yjdF motif RNAs is activated by Harmine and leads to robust reporter gene expressions in B
  • subtilis .

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