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5545716

Tocris Bioscience™ BMS 195614

Selective RARα antagonist

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Purity

>98%

Product Type

BMS 195614

Inhibitors

BMS 195614

Gene Alias

BMS614

Molecular Weight (g/mol)

448.51

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Description

  • Neutral retinoic acid receptor (RAR) α-selective antagonist (Ki = 2.5 nM)
  • Displays no significant effect on nuclear receptor corepressor (NCoR) binding; moderately decreases SMRT binding to RAR
  • Antagonizes agonist-induced coactivator (CoA) recruitment.

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