5545751

Tocris Bioscience™ Cladribine

Deoxyadenosine analog; pro-apoptotic

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Purity

>99%

Product Type

Cladribine

Molecular Weight (g/mol)

285.69

Inhibitors

Cladribine

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Description

  • Adenosine deaminase (ADA)-resistant analog of deoxyadenosine
  • Exhibits anti-leukemic activity; Inhibits cell growth of lymphoid and myeloid neoplasm (IC50 = 20 - 87 nM)
  • Pro-apoptotic; induces DNA double-strand breaks
  • Also inhibits ribonuclease reductase (IC50 = 0.11 - 0.28 μM)
  • Displays activity in vitro and in vivo
  • Orally bioavailable.

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