5545775

Tocris Bioscience™ E 64

Potent and irreversible cysteine protease inhibitor

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Purity

>98%

Product Type

E 64

Molecular Weight (g/mol)

357.41

Inhibitors

E 64

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Description

  • Potent and irreversible cysteine protease inhibitor (IC50 values are 1.4, 2.5 and 4.1 nM for cathepsin K, L and S respectively
  • Also inhibits papain, calpain, cathepsin B and cathepsin H
  • Has no effect on serine proteases
  • Reduces HSC-3 tongue cancer cell invasion and induces oxidative stress and apoptosis in filarial parasites
  • Also inhibits autophagy-associated lysosomal degradation in vitro .

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