5545865

Tocris Bioscience™ LM11A 31 dihydrochloride

Nonpeptide p75NTR ligand; neuroprotective

Manufacturer: Fischer Scientific

CAS Number: 1243259-19-9

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Purity

95%

CAS

1243259-19-9

Product Type

LM11A 31 dihydrochloride

Inhibitors

LM11A 31 dihydrochloride

Molecular Formula

(2 S,3 S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamide dihydrochloride

Content And Storage

Desiccate at RT

Molecular Weight (g/mol)

M.W. (Observed): 316.27

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Description

  • Nonpeptide p75NTR ligand; blocks p75-mediated cell death and also increases proliferation and survival of hippocampal neural progenitors
  • Exhibits no effect on nerve growth factor (NGF) binding to TrkA
  • Prevents and reverses atrophy of cholinergic neurites, as well as reversing Alzheimer's Disease (AD) pathologies in mid- to late-stage AD mice models
  • Shown to promote functional recovery in a mouse model of spinal cord injury
  • Orally available and brain penetrant.

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Nonpeptide p75NTR ligand; neuroprot...


Purity:
95%

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1243259-19-9

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Inhibitors:
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Molecular Formula:
(2 S,3 S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamide dihydrochloride

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Molecular Weight (g/mol):
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