5545868

Tocris Bioscience™ LU AA33810

Potent NPY Y5 receptor antagonist

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Purity

>98%

Product Type

LU AA33810

Molecular Weight (g/mol)

423.62

Inhibitors

LU AA33810

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Description

  • Potent neuropeptide Y (NPY) Y5 receptor antagonist (Ki = 1.5 nM in vitro )
  • Displays ≥ 3300-fold affinity for Y5 over Y1, Y2 and Y4 receptors
  • Also binds human 5-HT2B and 5-HT1A receptors (Ki values are 247 and 478 nM respectively)
  • Exerts anxiolytic- and antidepressant-like effects in rat models of stress sensitivity.

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