5546010

Tocris Bioscience™ SB 297006

Potent and selective CCR3 antagonist

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Purity

>99%

Product Type

SB 297006

Molecular Weight (g/mol)

342.35

Inhibitors

SB 297006

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Description

  • Potent and selective CCR3 antagonist (IC50 = 39 nM)
  • Displays 250-fold selectivity for CCR3 over other chemokine receptors, including CXCR1, CXCR2, CCR1 and CCR7 (IC50 >27 μM)
  • Inhibits calcium mobilization induced by MCP-4, eotaxin-2 and eotaxin in RBL-2H3 cells transfected with CCR3 (IC50 values are 80, 90 and 210 nM respectively).

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