50-001-0

Tocris Bioscience™ FTIDC

Manufacturer: Tocris Bioscience™

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Pack Size SKU Availability Price
Each of 1 50-001-0-Each-of-1 In Stock ₹ 41,684.83

50-001-0 - Each of 1

₹ 41,684.83

In Stock

Quantity

1

Base Price: ₹ 41,684.83

GST (18%): ₹ 7,503.269

Total Price: ₹ 49,188.099

Purity

>98%

Product Type

FTIDC

Inhibitors

FTIDC

Quantity

10 mg

Molecular Weight (g/mol)

358.41

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Description

  • FTIDC is a potent and selective mGlu1 receptor negative allosteric modulator (IC50 values are 5.8 and 6200 nM for mGlu1 and mGlu5 respectively)
  • Also acts as an mGlu1 receptor inverse agonist (IC50 = 7 nM) in the absence of ligand
  • Exhibits no effect at group II/III mGlu receptors
  • Inhibits L-glutamate-induced increases in intracellular calcium in mGlu1-expressing CHO cells
  • Inhibits nociceptive behavior, and exhibits anxiolytic and antipsychotic effects in vivo
  • Orally active.

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