5546128

Tocris Bioscience™ AC 5216

Selective TSPO ligand

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Purity

>98%

Product Type

AC 5216

Molecular Weight (g/mol)

401.46

Inhibitors

AC 5216

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Description

  • Ligand of translocator protein (TSPO, peripheral benzodiazepine receptor)
  • Exhibits high affinity for TSPO in rat whole brain (Ki = 0.297 nM), and high potency against human and rat glial TSPO (IC50 values are 2.73 and 3.04 nM respectively)
  • Displays no noticeable binding to a number of other receptors, transporters or ion channels
  • Also displays anxiolytic and antidepressant effects in rodent models, without inducing benzodiazepine-like adverse effects.

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