5546165
Tocris Bioscience™ JNJ 47965567
Potent and selective P2X7 antagonist; brain penetrant
Manufacturer: Fischer Scientific
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Purity
>98%
Product Type
JNJ 47965567
Molecular Weight (g/mol)
488.64
Inhibitors
JNJ 47965567
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Description
- Potent and selective P2X7 antagonist (pIC50 values are 8.3, 7.5 and 7.2 for human, mouse and rat receptors respectively)
- Selective over a panel of 50 other receptors, ion channels and transporters
- Reduces BzATP -induced IL-1β release from monocytes in vitro and from rat brain in vivo
- Attenuates amphetamine -induced hyperactivity in rats
- Brain penetrant.
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Purity: >98%
Product Type: JNJ 47965567
Molecular Weight (g/mol): 488.64
Inhibitors: JNJ 47965567
Purity:
>98%
Product Type:
JNJ 47965567
Molecular Weight (g/mol):
488.64
Inhibitors:
JNJ 47965567
Purity: >99%
Product Type: M8 B hydrochloride
Molecular Weight (g/mol): 432.96
Inhibitors: M8 B hydrochloride
Purity:
>99%
Product Type:
M8 B hydrochloride
Molecular Weight (g/mol):
432.96
Inhibitors:
M8 B hydrochloride
Purity: >99%
Product Type: ML 297
Molecular Weight (g/mol): 328.32
Inhibitors: ML 297
Purity:
>99%
Product Type:
ML 297
Molecular Weight (g/mol):
328.32
Inhibitors:
ML 297
Purity: >98%
Product Type: ML 349
Molecular Weight (g/mol): 454.56
Inhibitors: ML 349
Purity:
>98%
Product Type:
ML 349
Molecular Weight (g/mol):
454.56
Inhibitors:
ML 349