5546166

Tocris Bioscience™ M8 B hydrochloride

Potent and selective TRPM8 channel blocker

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Purity

>99%

Product Type

M8 B hydrochloride

Molecular Weight (g/mol)

432.96

Inhibitors

M8 B hydrochloride

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Description

  • Potent and selective TRPM8 channel blocker
  • Blocks cold- and icilin -induced TRPM8 activation in vitro (IC50 values are 7.8 and 26.9 nM respectively)
  • Exhibits no effect at other TRP channels (IC50 > 20 μM)
  • Reduces body temperature in vivo .

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