5546206
Tocris Bioscience™ UNC 1999
Potent and selective EZH2/EZH1 inhibitor
Manufacturer: Fischer Scientific
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Purity
>99%
Product Type
UNC 1999
Molecular Weight (g/mol)
569.74
Inhibitors
UNC 1999
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Description
- Potent and SAM-competitive EZH2/EZH1 lysine methyltransferase inhibitor (IC50 values are 10 and 45 nM, respectively)
- Selective for EZH2/EZH1 over a panel of other methyltransferases and non-epigenetic targets
- Reduces H3K27me3 levels in vitro
- Prolongs survival of MLL-AF9 bearing mice
- Orally bioavailable
- Negative Control also available.
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Purity: >99%
Product Type: UNC 1999
Molecular Weight (g/mol): 569.74
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