PV4901

Fluorescein-ERM (LRRKtide)

Manufacturer: LIFE TECHNOLOGIES

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Pack Size SKU Availability Price
Each of 1 PV4901-Each-of-1 In Stock ₹ 87,784.56

PV4901 - Each of 1

₹ 87,784.56

In Stock

Quantity

1

Base Price: ₹ 87,784.56

GST (18%): ₹ 15,801.221

Total Price: ₹ 1,03,585.781

Amino Acid Sequence

Fluorescein-GAGRLGRDKYKTLRQIRQ

Content And Storage

400 μM Fluorescein-ERM (LRRKtide) peptide substrate in water. Store at -20°C and protect from light.

Quantity

1 mg

Substrate Properties

Peptide-Based Substrate

Target Enzyme

Serine/Threonine Kinases

Label or Dye

FITC (Fluorescein)

Shipping Condition

Dry Ice

Validated Kinases

LRRK2

Assay Entry

Biochemical terbium phospho-specific activity

Detection Method

Fluorescence

Substrate

ERM (LRRKtide)

Substrate Type

Kinase Substrate

Gene ID (Entrez)

120892

Molecular Weight (g/mol)

2475.8 Da

Target Entry

LRRK2 D1994A, LRRK2 R1441C, LRRK2 I2020T, LRRK2 G2019S, LRRK2

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Description

  • A fluorescein-labeled peptide substrate based upon ezrin/radixin/moesin (ERM) that is phosphorylated by LRRK2 and LRRK2 mutants
  • For use in combination with the LanthaScreen™ Tb-anti-ERM (pLRRKtide) Antibody (PV4899) to evalute inhibitors in medium to high throughput screening applications.

Compare Similar Items

Show Difference

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LIFE TECHNOLOGIES

PV4901

--


Amino Acid Sequence:
Fluorescein-GAGRLGRDKYKTLRQIRQ

Content And Storage:
400 μM Fluorescein-ERM (LRRKtide) peptide substrate in water. Store at -20°C and protect from light.

Quantity:
1 mg

Substrate Properties:
Peptide-Based Substrate

Target Enzyme:
Serine/Threonine Kinases

Label or Dye:
FITC (Fluorescein)

Shipping Condition:
Dry Ice

Validated Kinases:
LRRK2

Assay Entry:
Biochemical terbium phospho-specific activity

Detection Method:
Fluorescence

Substrate:
ERM (LRRKtide)

Substrate Type:
Kinase Substrate

Gene ID (Entrez):
120892

Molecular Weight (g/mol):
2475.8 Da

Target Entry:
LRRK2 D1994A, LRRK2 R1441C, LRRK2 I2020T, LRRK2 G2019S, LRRK2

Img

GVS

PV4HY00010

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Amino Acid Sequence:
__

Content And Storage:
__

Quantity:
__

Substrate Properties:
__

Target Enzyme:
__

Label or Dye:
__

Shipping Condition:
__

Validated Kinases:
__

Assay Entry:
__

Detection Method:
__

Substrate:
__

Substrate Type:
__

Gene ID (Entrez):
__

Molecular Weight (g/mol):
__

Target Entry:
__

Img

Thermo Scientific™

PV5090

--


Amino Acid Sequence:
YSPTSPSYSPTSPSYSPTSPSKKKK

Content And Storage:
2 mM CDK7/9tide peptide substrate in 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2and 1 mM EGTA.Store at -20°C.

Quantity:
1 mL

Substrate Properties:
Peptide-Based Substrate

Target Enzyme:
Serine/Threonine Kinases

Label or Dye:
__

Shipping Condition:
Dry Ice

Validated Kinases:
CDK7, CDK9

Assay Entry:
Biochemical ADP accumulation

Detection Method:
Fluorescence

Substrate:
peptide based upon the C-terminal tail of RNA Polymerase II

Substrate Type:
Kinase Substrate

Gene ID (Entrez):
1022, 3376

Molecular Weight (g/mol):
2689.9 Da

Target Entry:
CDK9/Cyclin T1, CDK7

Img

LIFE TECHNOLOGIES

PV5093

--


Amino Acid Sequence:
RLGRDKYKTLRQIRQ

Content And Storage:
2 mM ERM (LRRKtide) peptide substrate in 50 mM HEPES (pH 7.5), 0.01% Brij-35, 10 mM MgCl2and 1 mM EGTA. Store at -20°C.

Quantity:
1 mL

Substrate Properties:
Peptide-Based Substrate

Target Enzyme:
Serine/Threonine Kinases

Label or Dye:
__

Shipping Condition:
Dry Ice

Validated Kinases:
LRRK2

Assay Entry:
Biochemical ADP accumulation

Detection Method:
Fluorescence

Substrate:
peptide based upon ezrin/radixin/moesin (ERM)

Substrate Type:
Kinase Substrate

Gene ID (Entrez):
120892

Molecular Weight (g/mol):
1931.2 Da

Target Entry:
LRRK2 G2019S, LRRK2