Thermo Scientific™ PathoDX™ Strep A Grouping Latex

Description

• Use Thermo Scientific™ Remel™ PathoDx™ Strep A Grouping Latex with Strep Grouping Kits
• The PathoDx procedure utilizes a latex agglutination method in conjunction with a nitrous acid extraction procedure 1,2
• The IgG coupled to the latex is highly specific for a given streptococcal group antigen
• This method offers significant advantages over other streptococcal grouping procedures in terms of rapidity, simplicity, and convenience
• The streptococcal group carbohydrates of streptococcal group A is a complex antigen with a rhamnose oligosaccharide and differing side chains, consisting primarily of glucosamine, either acetylated or non-acetylated
• In the PathoDx procedure, specific antibody on latex particles reacts with, and agglutinates, streptococcal group antigen extracted from the bacterial cell wall
• The test is intended for use with streptococcal colonies that are betahemolytic on sheep blood agar or for use with pure streptococcal isolates in broth cultures
• The reagents are designed to give a positive (2+ or greater) agglutination with one to two 18 to 24 hour colonies for most beta-hemolytic streptococcal isolates
• Ready-to-use – Prepared reagents Easy-to-store – Store at 2-8°C Easy to interpret – The PathoDx Strep Grouping kit is designed to give a 2+ or greater agglutination reaction with the extract of one or two colonies of an 18 to 24 hour culture of streptococci of Lancefield group A (large colony variety) in 60 seconds for most streptococcal isolates
• In a negative test, a uniform milky appearance with no agglutination after 60 seconds
• Strep A Grouping Latex (Red Cap) contains 3.0mL of a suspension of synthetic blue latex particles coated with rabbit antibody IgG-sensitized with 0.098% sodium azide and 0.05% ProClin 300 ® as preservatives
• Not all products are available for sale in all territories
• Please inquire
• Remel™ and Oxoid™ products are now part of the Thermo Scientific brand.