BD BBL™ Coagulase Plasma, Rabbit, with Citrate

Description

• Identification of staphylococci is based on microscopic examination, colonial morphology and cultural and biochemical characteristics
• Staphylococci associated with acute infection can clot plasma
• The most widely used and generally accepted criterion for identification of these pathogenic organisms is based on the presence of the enzyme coagulase
• Staphylococcus aureus produces two types of coagulase, free and bound
• Free coagulase is an extracellular enzyme produced when the organism is cultured in broth
• Bound coagulase, also known as the clumping factor, remains attached to the cell wall of the organism
• In the direct tube test, free coagulase liberated from the cell acts on prothrombin in the coagulase plasma to give a thrombin-like product
• This product then acts on fibrinogen to form a fibrin clot
• Available in 10-tube packs that reconstitute to 3ml or 15ml for use in the Direct Tube Method Store reconstituted plasma at 2–8°C for up to 14 day, or aliquot and freeze promptly for up to 30 days