Liofilchem™ MTS™ Aztreonam-avibactam

Description

• Ready to use
• No preparation or dilution of antimicrobial agent is required Synergy Testing: MTS™ can be crossed for evaluating a critical assay such as the in vitro combination of antibiotics Rapid and Efficient: MTS™ is easy to set up and full range of MIC testing of 6 agents on a large plate takes no more than 5 minutes
• Solid Medium: Growth of organisms on agar better mimics in vitro conditions
• It is easy to visualize hetero resistant variants in a population and to detect mixed cultures and contamination
• Wide MIC Range: The MIC range of Each MTS™ gradient spans across 15 dilutions fulfilling pharmacokinetic needs, varying susceptibility of many organism groups and covers different MIC breakpoints used in different countries as recommended by various reference or expert groups
• Easy to Learn: Setting up MTS™ is as easy as setting up a disc test, an established procedure familiar to all laboratories worldwide for over 50 years
• Minimal training is required for clinical microbiology personnel
• Easy for New Agents: When MTS™ becomes available for new agents, these can be easily introduced into clinical routines, as MTS™ is a standalone single reagent not a panel product
• New agents are usually rapidly available in the MTS™ format compared to panel AST systems
• Clinically, new agents are becoming increasingly important to test and consider as alternative therapeutic options due to increasing resistance
• MIC Equivalent to Reference Values: Scientific references and the clinical testing for device approval has validated that MTS™ MIC values are substantially equivalent to reference values from the CLSI agar and broth microdilution methods
• Thus, MIC interpretive criteria from international standards can be directly applied to interpret MTS™ MIC results
• Improved MIC Precision: The precise MIC value in μg/ mL is read directly from MTS™
• MIC values from MTS™ have an inherent precision of 1/2 dilution due to the continuous gradient
• MTS™ provides an exact on scale MIC value that is not an in-between two-fold dilution value
• Flexible Media Choice: MTS™ can be used with several AST media provided that the medium supports growth of the organism and is defined and standardized for susceptibility testing
• In fact, MTS™ can be used as a quality control tool for checking different AST media, brand to brand and batch to batch
• Robust Technique: As a stable gradient technique, MTS™ is relatively tolerant to variations that can be daily encountered in the laboratory e.g
• inoculum variations and technician performance and can still generate good intra and inter laboratory reproducibility
• Quantitative Value: MTS™ generates quantitative MIC values that are needed to guide therapy selection for the individual patient
• Fastidious and Slow Growers: Unlike many automated systems, MTS™ can be used for fastidious organisms e.g
• anaerobes, and other slow growing organisms and incubation can vary from 1 to 5 days
• Direct Specimen Testing: Due to the gradient and method flexibility, MTS™ can be used to directly test positive blood cultures, CSF and sputum from cystic fibrosis patients and bronchial aspirates from VAP patients
• The extra day saved by testing the specimen directly can have significant impact in therapy management, patient care and hospital cost savings.