Thermo Scientific™ Pierce™ Streptavidin Coated High Capacity Plates

Description

• Pierce Streptavidin High Binding Capacity (HBC) Plates are prepared with an exclusive coating method that yields a streptavidin-coated plate with four to five times the binding capacity of other commercially available polystyrene assay plates
• Using a Pierce Streptavidin HBC Plate can result in an assay with a broader dynamic range and better linearity, leading to improved assay precision
• The plates are offered in several plate formats, plate colors, and coating volumes
• Thermo Scientific Pierce Streptavidin-Coated High-Capacity Plates are designed for the binding of biotinylated oligonucleotides and peptides with higher binding efficiency than other commercially available plates
• Pierce Streptavidin-coated plates are widely used for applications such as ELISAs and other assay protocols
• These biotin-binding plates come with different capacities and sensitivities for maximum flexibility
• For example, the high-binding-capacity plates (HBC) can be used for anti-therapeutic/anti-drug antibodies (ADA) screening for immunogenicity research and biologics development (1,2)
• Both regular and HBC plates have been used in aptamer assays for clinical and industrial needs, along with neurobiology research for therapeutics and prevention, amongst other applications (3–5)
• Features of Streptavidin-Coated High-Capacity Plates include: • Unique plate-coating technology —results in high loading and binding capacity • Streptavidin-coated option —plates have up to five times the binding capacity of typical plates • Broader dynamic range —extends the quantitative range so there is less need for dilutions • Save time —pre-blocked plates to reduce the number of assay steps • Flexible assay formats —coated plates offered in 8-well strips to reduce waste The proprietary plate-coating technology used to manufacture these Pierce coated plates yields high-capacity plates with a wider detection limit than regular-binding-capacity plates
• The standard curve exhibits greater linearity for detecting small biotinylated molecules such as peptides and oligonucleotides, resulting in greater assay precision
• References 1
• J Immunol Methods
• 2016 Apr;431:45-51 2
• J Immunol Methods
• 2011 Feb 28;365(1-2):38-49 3
• Cancers (Basel)
• 2022 Oct 25;14(21):5222 4
• J Microbiol Biotechnol
• 2013 Jun 28;23(6):878-84 5
• Acta Neuropathol Commun
• 2018 May 31;6(1):43