M7824

Methotrexate

Manufacturer: SAFC

CAS Number: 59-05-2

Synonym(S): Methotrexate, (+)-Amethopterin, 4-Amino-10-methylfolic acid, 4-Amino-N10-methylpteroyl-L-glutamic acid, Antifolan, MTX, Methylaminopterin

Select a Size

Pack Size SKU Availability Price
1 G M7824-1-G In Stock ₹ 3,39,866.46
5 G M7824-5-G In Stock ₹ 14,68,403.46

M7824 - 1 G

₹ 3,39,866.46

In Stock

Quantity

1

Base Price: ₹ 3,39,866.46

GST (18%): ₹ 61,175.963

Total Price: ₹ 4,01,042.423

biological source

synthetic

Quality Level

400

form

powder

suitability

suitable for manufacturing use

storage temp.

−20°C

SMILES string

CN(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O

InChI

1S/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27)/t13-/m0/s1

InChI key

FBOZXECLQNJBKD-ZDUSSCGKSA-N

Gene Information

human ... DHFR(1719)

Other Options

Image Product Name Manufacturer Price Range
50-164-7348
Indofine Chemical METHOTREXATE, Products for Life Science, 59-05-2, 100 mg
Indofine Chemical ₹ 6,395.61
50-226-0861
Medchemexpress LLC HY-14519 500mg , Methotrexate CAS:59-05-2 Purity:>98%
Medchemexpress LLC ₹ 15,452.14
45-412-6100MG
MilliporeSigma™ Calbiochem™ Methotrexate
MilliporeSigma™ ₹ 11,745.68
NC0929277
Selleck Chemical LLC Methotrexate 100mg 59-05-2 NCI-C04671
Selleck Chemical LLC ₹ 15,092.78
NC1977802
Sigma Aldrich Fine Chemicals Biosciences Methotrexate United States Pharmacopeia (USP) Reference Standard | 59-05-2 | MFCD00064370 | 500MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 45,791.71
NC0472397
Cayman Chemical Methotrexate, 59-05-2, 100 mg
Cayman Chemical ₹ 4,620.24
NC0634286
Selleck Chemical LLC Methotrexate 10mM/1mL 59-05-2 NCI-C04671
Selleck Chemical LLC ₹ 20,226.38
M-136
Methotrexate solution
Supelco ₹ 10,068.10
PHR1396
Methotrexate
Supelco ₹ 12,165.60
1414003
Methotrexate
Sigma Aldrich ₹ 41,791.50

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Description

  • General description: Inhibits thymidylate synthetase, is a nonselective de novo purine synthesis inhibitor and has a significant toxicity profile including hepatotoxicity, pneumonitis and bone marrow suppression. Potent folic acid antagonist. Induces apoptosis in HL-60 human leukemia cells. Also useful as an anti-tumor agent.
  • Legal Information: SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFETY INFORMATION

Pictograms

GHS06,GHS08

Signal Word

Danger

Hazard Statements

H301,H341,H360D,H372

Precautionary Statements

P202 - P260 - P264 - P280 - P301 + P310 - P405

Hazard Classifications

Acute Tox. 3 Oral - Muta. 2 - Repr. 1B - STOT RE 1

Target Organs

Liver,Bone marrow

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Compare Similar Items

Show Difference

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SAFC

M7824

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biological source:
synthetic

Quality Level:
400

form:
powder

suitability:
suitable for manufacturing use

storage temp.:
−20°C

SMILES string:
CN(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O

InChI:
1S/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27)/t13-/m0/s1

InChI key:
FBOZXECLQNJBKD-ZDUSSCGKSA-N

Gene Information:
human ... DHFR(1719)

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M7899

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__

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SMILES string:
O.[Mn++].[O-]S([O-])(=O)=O

InChI:
1S/Mn.H2O4S.H2O/c;1-5(2,3)4;/h;(H2,1,2,3,4);1H2/q+2;;/p-2

InChI key:
ISPYRSDWRDQNSW-UHFFFAOYSA-L

Gene Information:
__

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Invitrogen™

M7901

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biological source:
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Quality Level:
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suitability:
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storage temp.:
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SMILES string:
__

InChI:
__

InChI key:
__

Gene Information:
__

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Sigma Aldrich

M79204

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biological source:
__

Quality Level:
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form:
liquid

suitability:
__

storage temp.:
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SMILES string:
CN1CCCC1

InChI:
1S/C5H11N/c1-6-4-2-3-5-6/h2-5H2,1H3

InChI key:
AVFZOVWCLRSYKC-UHFFFAOYSA-N

Gene Information:
__