200006990

Tocris Bioscience™ ML 162

Inhibits glutathione peroxidase (GPX4); induces ferroptosis

Manufacturer: Fischer Scientific

CAS Number: 1035072-16-2

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Chemical Name or Material

2-[(Chloroacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thien-2-ylacetamide

Target

Glutathione Peroxidase 4/GPX4

Purity

0.98

CAS

1035072-16-2

Molecular Formula

C23H22Cl2N2O3S

Other Options

Image Product Name Manufacturer Price Range
78-211-0
Tocris Bioscience™ ML 162
Fischer Scientific ₹ 15,948.38
78-215-0
Tocris Bioscience™ ML 162
Fischer Scientific ₹ 64,897.26
50-225-8948
Medchemexpress LLC HY-100002 5mg ,ML162 CAS:1035072-16-2 Purity:>98%
Medchemexpress LLC ₹ 9,882.18
AX65758
1035072-16-2 | α-[(2-chloroacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thiopheneacetamide
A2B Chem ₹ 2,224.56 - ₹ 13,518.48

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Description

  • ML 162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor
  • It induces ferroptosis in vivo
  • It is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50 = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively).

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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2-[(Chloroacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thien-2-ylacetamide

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C23H22Cl2N2O3S

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