200007290
Tocris Bioscience™ TM2 TEAD inhibitor
Potent and reversible inhibitor of TEAD mediated Hippo/Yap signalling
Manufacturer: Fischer Scientific
CAS Number: 1008768-41-9
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Chemical Name or Material
4-[3-(2-Cyclohexylethoxy)benzoyl]-N-phenyl-1-piperazinecarboxamide
Target
YAP1
Purity
0.98
CAS
1008768-41-9
Molecular Formula
C26H33N3O3
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ TM2 TEAD inhibitor | Fischer Scientific | ₹ 12,851.60 | |
| | Tocris Bioscience™ TM2 TEAD inhibitor | Fischer Scientific | ₹ 54,156.50 | |
 | 1008768-41-9 | TEAD-IN-8 | A2B Chem | -- |
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Description
- TM2 TEAD inhibitor is a potent and reversible TEA domain transcription factor inhibitor (IC50 = 38 nM and 156 nM for TEAD4 auto-palmitoylation and TEAD2 palmitoylation, respectively)
- It inhibits TEAD-YAP association and transcriptional activity
- TM2 TEAD inhibitor exhibits strong antiproliferation effects as a single agent or in combination with a MEK inhibitor in YAP-dependent cancer cells
- Also inhibits YAP-dependent liver organoid growth ex vivo .
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: 4-[3-(2-Cyclohexylethoxy)benzoyl]-N-phenyl-1-piperazinecarboxamide
Target: YAP1
Purity: 0.98
CAS: 1008768-41-9
Molecular Formula: C26H33N3O3
Chemical Name or Material:
4-[3-(2-Cyclohexylethoxy)benzoyl]-N-phenyl-1-piperazinecarboxamide
Target:
YAP1
Purity:
0.98
CAS:
1008768-41-9
Molecular Formula:
C26H33N3O3
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