4785442

Tocris Bioscience™ Ro 25-6981 maleate

GluN2B-selective NMDA antagonist

Manufacturer: Fischer Scientific

CAS Number: 1312991-76-6

The price for this product is unavailable. Please request a quote

Chemical Name or Material

(αR,βS)-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol maleate

Assay Percent Range

>98%

Molecular Formula

C22H29NO2.C4H4O4

CAS

1312991-76-6

Solubility

Soluble to 100mM in DMSO

Formula Weight

Observed MW: 455.55

Related Products

Img

Fischer Scientific

15-941-R

--

Img

Fischer Scientific

15-941-0

--

Img

Fischer Scientific

15-945-0

--

Img

Fischer Scientific

62-221-0

--

Img

Fischer Scientific

08-221-0

--

Img

Fischer Scientific

08-225-0

--

Img

Fischer Scientific

62-225-0

--

Img

Fischer Scientific

12-121-0

--

Description

  • Potent and selective activity-dependent blocker of NMDA receptors containing the GluN2B (formally NR2B) subunit
  • IC50 values are 0.009 and 52 μM for cloned receptor subunit combinations GluN1C/GluN2B and GluN1C/GluN2A respectively
  • Displays neuroprotectant effects in vivo and in vitro
  • Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions .

SAFETY INFORMATION

  • Recommended Storage : Desiccate at Room Temperature