63-131-0

Tocris™ A 33

Manufacturer: Tocris™

CAS Number: 915082-52-9

Select a Size

Pack Size SKU Availability Price
Each of 1 63-131-0-Each-of-1 In Stock ₹ 21,475.56

63-131-0 - Each of 1

₹ 21,475.56

In Stock

Quantity

1

Base Price: ₹ 21,475.56

GST (18%): ₹ 3,865.601

Total Price: ₹ 25,341.161

Chemical Name or Material

2-[4-[[2-(5-Chloro-2-thienyl)-5-ethyl-6-methyl-pyrimidin-4-yl]amino]phenyl]acetic acid

Quantity

10 mg

Formula Weight

387.88

Purity

98%

CAS

915082-52-9

Molecular Formula

C19H18ClN3O2S

Product Type

Inhibitor

Other Options

Image Product Name Manufacturer Price Range
50-186-9663
Sigma Aldrich Fine Chemicals Biosciences A-33 >=98% (HPLC) | 915082-52-9 | 25MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 44,764.99
50-186-9664
Sigma Aldrich Fine Chemicals Biosciences A-33 >=98% (HPLC) | 915082-52-9 | 5MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 11,319.59
50-245-2293
eMolecules​ Medchem Express / PDE4B-IN-2 / 5mg / 632433182 / HY-115687 / / 915082-52-9 / [null] / 387.880 / C19H18ClN3O2S
eMolecules​ ₹ 11,334.99
CS-0120739
PDE4B-IN-2
ChemScene ₹ 7,700.40 - ₹ 61,603.20
BA88348
915082-52-9 | A 33
A2B Chem ₹ 2,053.44 - ₹ 39,357.60

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Description

  • A 33 is a potent and selective PDE4B inhibitor (IC50 = 15 nM); exhibits >100-fold selectivity for PDE4B over 4D
  • Regulates cAMP in inflammatory cells
  • Inhibits LPS-induced TNF-α production and neutrophil accumulation in mouse lungs
  • Reduces microglial and neutrophil activation, and improves behavioral deficits in a traumatic brain injury model in vivo
  • Also exhibits antidepressant-like effects
  • Orally bioavailable.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Tocris™

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Chemical Name or Material:
2-[4-[[2-(5-Chloro-2-thienyl)-5-ethyl-6-methyl-pyrimidin-4-yl]amino]phenyl]acetic acid

Quantity:
10 mg

Formula Weight:
387.88

Purity:
98%

CAS:
915082-52-9

Molecular Formula:
C19H18ClN3O2S

Product Type:
Inhibitor

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