67-411-0
Tocris™ GW 4869
Manufacturer: Tocris™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 67-411-0-Each-of-1 | In Stock | ₹ 26,522.00 |
67-411-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 26,522.00
GST (18%): ₹ 4,773.96
Total Price: ₹ 31,295.96
Chemical Name or Material
3,3 '-(1,4-Phenylene)bis[N-[4-(4,5-dihydro-1 H-imidazol-2-yl)phenyl]-2-propenamide] ditrifluoroacetate
Target
Hydrolase Inhibitors
Purity
0.9
Quantity
10 mg
Molecular Formula
C30H28N6O20.2 CF3COOH
Related Products
Description
- GW 4869 is a selective neutral sphingomyelin phosphodiesterase (N-SMase) inhibitor (IC50 = 1 μM)
- Exhibits selectivity for neutral sphingomyelinase over acid sphingomyelinase (a-SMase) at concentrations up to 150 μM as well as B
- cereus PC-PLC, human lyso-PAF PLC, and bovine PP2A at 10 μM
- Blocks exosome biogenesis
- Inhibits TNF-α-induced sphingomyelin hydrolysis and TNF-α-induced cell death in MCF-7 cells
- Reverses hypoxia-induced pulmonary vasoconstriction in rats
- Neuroprotective.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: 3,3 '-(1,4-Phenylene)bis[N-[4-(4,5-dihydro-1 H-imidazol-2-yl)phenyl]-2-propenamide] ditrifluoroacetate
Target: Hydrolase Inhibitors
Purity: 0.9
Quantity: 10 mg
Molecular Formula: C30H28N6O20.2 CF3COOH
Chemical Name or Material:
3,3 '-(1,4-Phenylene)bis[N-[4-(4,5-dihydro-1 H-imidazol-2-yl)phenyl]-2-propenamide] ditrifluoroacetate
Target:
Hydrolase Inhibitors
Purity:
0.9
Quantity:
10 mg
Molecular Formula:
C30H28N6O20.2 CF3COOH
Chemical Name or Material: __
Target: __
Purity: __
Quantity: 100 μg
Molecular Formula: __
Chemical Name or Material:
__
Target:
__
Purity:
__
Quantity:
100 μg
Molecular Formula:
__
Chemical Name or Material: N-(2-(2-(2-(4-(4-((5-Chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-5-isopropoxy-2-methylphenyl)piperidin-1-yl)ethoxy)ethoxy)ethyl)-2-((1,3-dioxo-2-(2-oxopiperidin-3-yl)isoindolin-4-yl)amino)acetamide
Target: __
Purity: 98%
Quantity: 5 mg
Molecular Formula: C49H62ClN9O9S
Chemical Name or Material:
N-(2-(2-(2-(4-(4-((5-Chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-5-isopropoxy-2-methylphenyl)piperidin-1-yl)ethoxy)ethoxy)ethyl)-2-((1,3-dioxo-2-(2-oxopiperidin-3-yl)isoindolin-4-yl)amino)acetamide
Target:
__
Purity:
98%
Quantity:
5 mg
Molecular Formula:
C49H62ClN9O9S
Chemical Name or Material: __
Target: __
Purity: __
Quantity: 25μg
Molecular Formula: __
Chemical Name or Material:
__
Target:
__
Purity:
__
Quantity:
25μg
Molecular Formula:
__