68-955-0
Tocris Bioscience™ VU 0424465
Manufacturer: Fischer Scientific
CAS Number: 1428630-85-6
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 68-955-0-Each-of-1 | In Stock | ₹ 95,577.36 |
68-955-0 - Each of 1
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Quantity
1
Base Price: ₹ 95,577.36
GST (18%): ₹ 17,203.925
Total Price: ₹ 1,12,781.285
Chemical Name or Material
5-[2-(2-(3-Fluorophenyl)ethynyl]-N-[(1R)-2-hydroxy-1,2-dimethylpropyl]-2-pyridinecarboxamide
Quantity
50 mg
Purity
98%
CAS
1428630-85-6
Molecular Formula
C19H19FN2O2
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| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ VU 0424465 | Fischer Scientific | -- | |
 | Tocris Bioscience™ VU 0424465 | Fischer Scientific | ₹ 22,926.66 |
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Description
- Potent mGlu5 positive allosteric modulator (EC50 = 1.5 nM) and agonist (EC50 = 171 nM; maximum effect is 65% that of glutamate)
- Binds allosteric site with high affinity (Ki = 11.8 nM)
- Increases maximum response to glutamate by 30%
- Exhibits bias towards signaling via IP1 and ERK1/2 over iCa2+ in HEK293 and neuronal cells, and activates Gs in HEK 293 cells
- Induces epileptiform activity in CA3 hippocampal neurons in vitro and convulsions in vivo .
Compare Similar Items
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Chemical Name or Material: 5-[2-(2-(3-Fluorophenyl)ethynyl]-N-[(1R)-2-hydroxy-1,2-dimethylpropyl]-2-pyridinecarboxamide
Quantity: 50 mg
Purity: 98%
CAS: 1428630-85-6
Molecular Formula: C19H19FN2O2
Chemical Name or Material:
5-[2-(2-(3-Fluorophenyl)ethynyl]-N-[(1R)-2-hydroxy-1,2-dimethylpropyl]-2-pyridinecarboxamide
Quantity:
50 mg
Purity:
98%
CAS:
1428630-85-6
Molecular Formula:
C19H19FN2O2
Chemical Name or Material: 2-[1-(4-Chlorophenyl)cyclopropyl]-4,5-dihydro-7-iodo-5-oxopyrazolo[1,5-a]quinazoline-3-carbonitrile
Quantity: 25 mg
Purity: 98%
CAS: 2226517-75-3
Molecular Formula: C20H12ClIN4O
Chemical Name or Material:
2-[1-(4-Chlorophenyl)cyclopropyl]-4,5-dihydro-7-iodo-5-oxopyrazolo[1,5-a]quinazoline-3-carbonitrile
Quantity:
25 mg
Purity:
98%
CAS:
2226517-75-3
Molecular Formula:
C20H12ClIN4O
Chemical Name or Material: 2-[1-(4-Chlorophenyl)cyclopropyl]-4,5-dihydro-7-iodo-5-oxopyrazolo[1,5-a]quinazoline-3-carbonitrile
Quantity: 5 mg
Purity: 98%
CAS: 2226517-75-3
Molecular Formula: C20H12ClIN4O
Chemical Name or Material:
2-[1-(4-Chlorophenyl)cyclopropyl]-4,5-dihydro-7-iodo-5-oxopyrazolo[1,5-a]quinazoline-3-carbonitrile
Quantity:
5 mg
Purity:
98%
CAS:
2226517-75-3
Molecular Formula:
C20H12ClIN4O
Chemical Name or Material: 4-Chloro-2-(1-(2-(2,4,6-trichlorophenyl)hydrazono)ethyl)phenol
Quantity: 25 mg
Purity: 98%
CAS: 219315-22-7
Molecular Formula: C14H10Cl4N2O
Chemical Name or Material:
4-Chloro-2-(1-(2-(2,4,6-trichlorophenyl)hydrazono)ethyl)phenol
Quantity:
25 mg
Purity:
98%
CAS:
219315-22-7
Molecular Formula:
C14H10Cl4N2O