69-031-0

Tocris™ DPTIP

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 69-031-0-Each-of-1 In Stock ₹ 23,486.22

69-031-0 - Each of 1

₹ 23,486.22

In Stock

Quantity

1

Base Price: ₹ 23,486.22

GST (18%): ₹ 4,227.52

Total Price: ₹ 27,713.74

Quantity

10 mg

Formula Weight

378.45

Purity

98%

Molecular Formula

C21H18N2O3S

Product Type

Inhibitor

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Description

  • DPTIP is a potent and selective sphingomyelin phosphodiesterase (N-SMase2) inhibitor (IC50 = 30 nM)
  • Exhibits no inhibition of related enzymes alkaline phosphatase, phosphomonoesterase or acid sphingomyelinase
  • Inhibits extracellular vesicle (EV) release in primary astrocyte cultures and in vivo
  • Attenuates IL-1β-induced astrocyte-derived EV release in a mouse model of brain injury and suppresses infiltration of immune cells into the brain
  • Metabolically stable and brain penetrant.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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