69-341-0

Tocris™ 673 A

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Quantity

10 mg

Formula Weight

223.28

Purity

98%

Molecular Formula

C15H13NO

Product Type

Inhibitor

Related Products

Img

Fischer Scientific

69-345-0

--

Img

Fischer Scientific

68-681-0

--

Img

Fischer Scientific

63-405

--

Img

Fischer Scientific

68-685-0

--

Img

Fischer Scientific

68-841-0

--

Img

Fischer Scientific

69-331-0

--

Img

Fischer Scientific

63-402-5

--

Img

Fischer Scientific

68-845-0

--

Description

  • 673 A is an aldehyde dehydrogenase (ALDH1A) inhibitor (IC50 values are 230, 246 and 348 nM for ALDH1A2, ALDH1A1 and ALDH1A3, respectively)
  • Exhibits >40-fold selectivity for ALD1A over ALDH2
  • Depletes CD133+ cancer stem cells (CSC) in ovarian cancer cell lines
  • Triggers necroptosis in ovarian CSCs and induces expression of mitochondrial uncoupling proteins (UCP)
  • Overcomes chemotherapy resistance in vivo .

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

Compare Similar Items

Show Difference

Img

Fischer Scientific

69-341-0

--


Quantity:
10 mg

Formula Weight:
223.28

Purity:
98%

Molecular Formula:
C15H13NO

Product Type:
Inhibitor

Img

Fischer Scientific

69-345-0

--


Quantity:
50 mg

Formula Weight:
223.28

Purity:
98%

Molecular Formula:
C15H13NO

Product Type:
Inhibitor

Img

MilliporeSigma™

69-348-3

--


Quantity:
500 pmol

Formula Weight:
__

Purity:
__

Molecular Formula:
__

Product Type:
T7 Promoter Primer

Img

Tocris Bioscience™

69-365

--


Quantity:
5 mg

Formula Weight:
__

Purity:
98%

Molecular Formula:
C53H67FN8O8S

Product Type:
__