7082172
Tocris Bioscience™ TC-G 1005
Potent and selective GPBA receptor (TGR5) agonist
Manufacturer: Fischer Scientific
CAS Number: 1415407-60-1
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Chemical Name or Material
TC-G 1005
Synonym
(4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone
Molecular Formula
C25H25N3O2
Physical Form
Solid
Purity
>98%
CAS
1415407-60-1
Solubility
Soluble to 100mM in DMSO and to 100mM in ethanol
Formula Weight
399.48
Product Type
Bioactive Small Molecule
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ TC-G 1005 | Fischer Scientific | ₹ 29,090.40 | |
| | Tocris Bioscience™ TC-G 1005 | Fischer Scientific | ₹ 1,23,463.08 | |
 | Medchemexpress LLC HY-110173 5mg Medchemexpress, TC-G 1005 CAS:1415407-60-1 Purity:>98% | Medchemexpress LLC | ₹ 11,678.94 | |
 | eMolecules Medchem Express / TC-G 1005 / 5mg / 572596504 / HY-110173 / / 1415407-60-1 / MFCD30182262 / 399.494 / C25H25N3O2 | eMolecules | ₹ 16,372.76 | |
 | (4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone | Aaron Chemicals LLC | ₹ 12,406.20 - ₹ 1,37,323.80 | |
 | 1415407-60-1 | (4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone | A2B Chem | ₹ 8,556.00 - ₹ 48,426.96 |
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Description
- Potent and selective GPBA agonist (EC50 = 0.72 nM for hTGR5)
- Selective for TGR5 over FXR (farnesoid X receptor)
- Increases plasma GLP-1 levels and reduces blood glucose in mice
- Orally available.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: TC-G 1005
Synonym: (4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone
Molecular Formula: C25H25N3O2
Physical Form: Solid
Purity: >98%
CAS: 1415407-60-1
Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
Formula Weight: 399.48
Product Type: Bioactive Small Molecule
Chemical Name or Material:
TC-G 1005
Synonym:
(4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone
Molecular Formula:
C25H25N3O2
Physical Form:
Solid
Purity:
>98%
CAS:
1415407-60-1
Solubility:
Soluble to 100mM in DMSO and to 100mM in ethanol
Formula Weight:
399.48
Product Type:
Bioactive Small Molecule
Chemical Name or Material: JTE 607 dihydrochloride
Synonym: N-[3,5-Dichloro-2-hydroxy-4-[2-(4-methyl-1-piperazinyl)ethoxy]benzoyl]-L-phenylalanine ethyl ester dihydrochloride
Molecular Formula: C25H31Cl2N3O5·2HCl
Physical Form: Solid
Purity: >98%
CAS: 188791-09-5
Solubility: Soluble to 100mM in water and to 100mM in DMSO
Formula Weight: 597.36
Product Type: Bioactive Small Molecule
Chemical Name or Material:
JTE 607 dihydrochloride
Synonym:
N-[3,5-Dichloro-2-hydroxy-4-[2-(4-methyl-1-piperazinyl)ethoxy]benzoyl]-L-phenylalanine ethyl ester dihydrochloride
Molecular Formula:
C25H31Cl2N3O5·2HCl
Physical Form:
Solid
Purity:
>98%
CAS:
188791-09-5
Solubility:
Soluble to 100mM in water and to 100mM in DMSO
Formula Weight:
597.36
Product Type:
Bioactive Small Molecule
Chemical Name or Material: NK 252
Synonym: N-[5-(2-Furanyl)-1,3,4-oxadiazol-2-yl]-N'-(2-pyridinylmethyl)urea
Molecular Formula: C13H11N5O3
Physical Form: Powder
Purity: >98%
CAS: 1414963-82-8
Solubility: Soluble to 100mM in 1eq. HCl and to 100mM in DMSO
Formula Weight: 285.26
Product Type: Bioactive Small Molecule
Chemical Name or Material:
NK 252
Synonym:
N-[5-(2-Furanyl)-1,3,4-oxadiazol-2-yl]-N'-(2-pyridinylmethyl)urea
Molecular Formula:
C13H11N5O3
Physical Form:
Powder
Purity:
>98%
CAS:
1414963-82-8
Solubility:
Soluble to 100mM in 1eq. HCl and to 100mM in DMSO
Formula Weight:
285.26
Product Type:
Bioactive Small Molecule
Chemical Name or Material: TC-I 2014
Synonym: 3-[7-(Trifluoromethyl)-5-[2-(trifluoromethyl)phenyl]-1H-benzimidazol-2-yl]-1-oxa-2-azaspiro[4.5]dec-2-ene
Molecular Formula: C23H19F6N3O
Physical Form: Powder
Purity: >98%
CAS: 1221349-53-6
Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
Formula Weight: 467.41
Product Type: Bioactive Small Molecule
Chemical Name or Material:
TC-I 2014
Synonym:
3-[7-(Trifluoromethyl)-5-[2-(trifluoromethyl)phenyl]-1H-benzimidazol-2-yl]-1-oxa-2-azaspiro[4.5]dec-2-ene
Molecular Formula:
C23H19F6N3O
Physical Form:
Powder
Purity:
>98%
CAS:
1221349-53-6
Solubility:
Soluble to 100mM in DMSO and to 100mM in ethanol
Formula Weight:
467.41
Product Type:
Bioactive Small Molecule